Cargando…

Probing milk extracellular vesicles for intestinal delivery of RNA therapies

BACKGROUND: Oral delivery remains unattainable for nucleic acid therapies. Many nanoparticle-based drug delivery systems have been investigated for this, but most suffer from poor gut stability, poor mucus diffusion and/or inefficient epithelial uptake. Extracellular vesicles from bovine milk (mEVs)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yunyue, Belaid, Mona, Luo, Xiang, Daci, Armond, Limani, Rinë, Mantaj, Julia, Zilbauer, Matthias, Nayak, Komal, Vllasaliu, Driton
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623793/ https://www.ncbi.nlm.nih.gov/pubmed/37924132 http://dx.doi.org/10.1186/s12951-023-02173-x

Ejemplares similares

Cow Milk and Intestinal Epithelial Cell-Derived Extracellular Vesicles as Systems for Enhancing Oral Drug Delivery
por: Carobolante, Greta, et al.
Publicado: (2020)

Ascorbyl Palmitate Hydrogel for Local, Intestinal Delivery of Macromolecules
por: Zhai, Jinyi, et al.
Publicado: (2018)

Delivery of Nanoparticles across the Intestinal Epithelium via the Transferrin Transport Pathway
por: Yong, Jing M., et al.
Publicado: (2019)

Evaluation of a Methylcellulose and Hyaluronic Acid Hydrogel as a Vehicle for Rectal Delivery of Biologics
por: Aprodu, Andreea, et al.
Publicado: (2019)

Nanoparticle modification in biological media: implications for oral nanomedicines
por: Muraleetharan, Vishnaka, et al.
Publicado: (2019)

Non-Invasive Drug Delivery Systems
por: Vllasaliu, Driton
Publicado: (2021)

Polymorphic Variants of SCN1A and EPHX1 Influence Plasma Carbamazepine Concentration, Metabolism and Pharmacoresistance in a Population of Kosovar Albanian Epileptic Patients
por: Daci, Armond, et al.
Publicado: (2015)

Pulmonary Delivery of Biological Drugs
por: Liang, Wanling, et al.
Publicado: (2020)

Cow Milk Extracellular Vesicle Effects on an In Vitro Model of Intestinal Inflammation
por: Mecocci, Samanta, et al.
Publicado: (2022)

Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency
por: Capel, Victoria, et al.
Publicado: (2016)

Extracellular Vesicles in Human Milk
por: Hu, Yong, et al.
Publicado: (2021)

Water-soluble substituted chitosan derivatives as technology platform for inhalation delivery of siRNA
por: Capel, Victoria, et al.
Publicado: (2018)

Nanotherapy for bone repair: milk-derived small extracellular vesicles delivery of icariin
por: Yu, Xinxin, et al.
Publicado: (2023)

Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis
por: Tong, Lingjun, et al.
Publicado: (2023)

Milk-Derived Extracellular Vesicles in Inter-Organism, Cross-Species Communication and Drug Delivery
por: Sanwlani, Rahul, et al.
Publicado: (2020)

Doxorubicin Loading into Milk and Mesenchymal Stem Cells’ Extracellular Vesicles as Drug Delivery Vehicles
por: Mukhopadhya, Anindya, et al.
Publicado: (2023)

Mechanism of Mucosal Permeability Enhancement of CriticalSorb® (Solutol® HS15) Investigated In Vitro in Cell Cultures
por: Shubber, Saif, et al.
Publicado: (2014)

Isolation of Bovine and Human Milk Extracellular Vesicles
por: Weiskirchen, Ralf, et al.
Publicado: (2023)

Toll-like Receptors and Cytokine Modulation by Goat Milk Extracellular Vesicles in a Model of Intestinal Inflammation
por: De Ciucis, Chiara Grazia, et al.
Publicado: (2023)

Microperforated Hymen Presenting Spontaneous Pregnancy with Cesarean Delivery and Hymenotomy Surgery: A Case Report
por: Elshani, Brikene, et al.
Publicado: (2018)

The Therapeutic Potential of Breast Milk-Derived Extracellular Vesicles
por: Galley, Jeffrey D., et al.
Publicado: (2020)

The Therapeutic Potential of Milk Extracellular Vesicles on Colorectal Cancer
por: Babaker, Manal A., et al.
Publicado: (2022)

Extracellular Vesicles: Delivery Vehicles of Myokines
por: Trovato, Eleonora, et al.
Publicado: (2019)

Porcine Milk-Derived Small Extracellular Vesicles Promote Intestinal Immunoglobulin Production through pIgR
por: Zeng, Bin, et al.
Publicado: (2021)

Small extracellular vesicles in cancer
por: Abhange, Komal, et al.
Publicado: (2021)

Defense Agents in Milk: A. Defense Agents in Human Milk
por: GOLDMAN, ARMOND S., et al.
Publicado: (1995)

Characterization of Sheep Milk Extracellular Vesicle-miRNA by Sequencing and Comparison with Cow Milk
por: Quan, Suyu, et al.
Publicado: (2020)

Biocompatibility of highly purified bovine milk-derived extracellular vesicles
por: Somiya, Masaharu, et al.
Publicado: (2018)

Acidification effects on isolation of extracellular vesicles from bovine milk
por: Rahman, Md. Matiur, et al.
Publicado: (2019)

Extracellular vesicle miRNAs in breast milk of obese mothers
por: Cho, Young Eun, et al.
Publicado: (2022)

Multifunctional Milk-Derived Small Extracellular Vesicles and Their Biomedical Applications
por: Zhong, Youxiu, et al.
Publicado: (2023)

Temporal Quantitative Proteomics Analysis of Neuroblastoma Cells Treated with Bovine Milk-Derived Extracellular Vesicles Highlights the Anti-Proliferative Properties of Milk-Derived Extracellular Vesicles
por: Fonseka, Pamali, et al.
Publicado: (2021)

Water-soluble extracellular vesicle probes based on conjugated oligoelectrolytes
por: Zhou, Cheng, et al.
Publicado: (2023)

Targeted delivery of extracellular vesicles in heart injury
por: Chen, Peier, et al.
Publicado: (2021)

Extracellular Vesicles as Drug Delivery Systems in Cancer
por: Hernandez-Oller, Laia, et al.
Publicado: (2020)

Reprogramming Extracellular Vesicles for Protein Therapeutics Delivery
por: Ovchinnikova, Leyla A., et al.
Publicado: (2021)

Extracellular Vesicles for Drug Delivery in Cancer Treatment
por: Wang, Li, et al.
Publicado: (2023)

Extracellular vesicle separation from milk and infant milk formula using acid precipitation and ultracentrifugation
por: Mukhopadhya, Anindya, et al.
Publicado: (2021)

Plant‐derived extracellular vesicles: Recent advancements and current challenges on their use for biomedical applications
por: Lian, Meredith Qikai, et al.
Publicado: (2022)

Invasive ductal carcinoma within fibroadenoma: a case report
por: Gashi-Luci, Lumturije H, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_hsdb9rvfr8sas4704bgvjan787