DNA damage response and repair gene mutations are associated with tumor mutational burden and outcomes to platinum-based chemotherapy/immunotherapy in advanced NSCLC patients

BACKGROUND: DNA damage response and repair (DDR) genes are crucial for maintaining the integrity of the genome. This study aims to explore the correlation of DDR gene mutations with TMB, clinical characteristics, and outcomes to platinum-based chemotherapy and platinum-based chemotherapy/immunothera...

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Detalles Bibliográficos
Autores principales: Gu, Weiguang, Zhuang, Wenya, Zhuang, Mengxia, He, Minhong, Li, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623851/
https://www.ncbi.nlm.nih.gov/pubmed/37924135
http://dx.doi.org/10.1186/s13000-023-01401-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623851/
https://www.ncbi.nlm.nih.gov/pubmed/37924135
http://dx.doi.org/10.1186/s13000-023-01401-0

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