Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a type of cancer with high morbidity and mortality rates worldwide. Owing to a lack of therapeutic options, the overall survival rate of patients with pancreatic cancer is low. Gemcitabine has been mainly used to treat patients with pancreatic cancer, but i...

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Detalles Bibliográficos
Autores principales: Kang, Hyeon Woong, Kim, Ju Hyun, Lee, Da Eun, Lee, Yun Sun, Kim, Myeong Jin, Kim, Hyung Sun, Fang, SungSoon, Lee, Bo Eun, Lee, Kyung Jin, Yoo, Jongman, Kim, Hyo Jung, Park, Joon Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623893/
https://www.ncbi.nlm.nih.gov/pubmed/37917550
http://dx.doi.org/10.1080/15384047.2023.2272334

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