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Robotic‐assisted colectomy for right‐sided colon cancer: Short‐term surgical outcomes of a multi‐institutional prospective cohort study in Japan

BACKGROUND: In Japan, there are no substantial reports on robotic‐assisted colectomy because few institutions performed the procedure, as it was not covered by national insurance until March 2022. AIM: This study aimed to evaluate the safety and feasibility of robotic‐assisted colectomy for patients...

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Autores principales: Yamauchi, Shinichi, Shiomi, Akio, Matsuda, Chu, Takemasa, Ichiro, Hanai, Tsunekazu, Uemura, Mamoru, Kinugasa, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623957/
https://www.ncbi.nlm.nih.gov/pubmed/37927933
http://dx.doi.org/10.1002/ags3.12694
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author Yamauchi, Shinichi
Shiomi, Akio
Matsuda, Chu
Takemasa, Ichiro
Hanai, Tsunekazu
Uemura, Mamoru
Kinugasa, Yusuke
author_facet Yamauchi, Shinichi
Shiomi, Akio
Matsuda, Chu
Takemasa, Ichiro
Hanai, Tsunekazu
Uemura, Mamoru
Kinugasa, Yusuke
author_sort Yamauchi, Shinichi
collection PubMed
description BACKGROUND: In Japan, there are no substantial reports on robotic‐assisted colectomy because few institutions performed the procedure, as it was not covered by national insurance until March 2022. AIM: This study aimed to evaluate the safety and feasibility of robotic‐assisted colectomy for patients with curatively resectable colon cancer in Japan. METHODS: This multi‐institutional, prospective, single‐arm, observational study enrolled patients diagnosed with curatively resectable clinical stage I–IIIC colon adenocarcinoma with D2 or D3 lymph node dissection and treated with robotic‐assisted colectomy. The primary endpoint was the conversion rate to laparotomy. The non‐inferiority of outcomes for robotic‐assisted colectomy versus laparoscopic colectomy, which was determined from historical data, was verified. RESULTS: One hundred patients were registered between July 2019 and March 2022 and underwent robotic‐assisted colectomy performed by seven expert surgeons at six institutions. Thirteen patients were excluded because their surgeons had insufficient experience performing robotic‐assisted colectomy; therefore, 87 patients were eligible for the primary endpoint analysis. There was no conversion in these 87 patients, and robotic‐assisted colectomy was non‐inferior to laparoscopic colectomy in terms of conversion rate (90% confidence interval 0–3.38, p = 0.0006). No intraoperative adverse events occurred, and no mortality was observed in a total of 100 patients. The rate of patients with Clavien–Dindo complications grade III or higher was 4%. CONCLUSION: This study showed the non‐inferiority of the conversion rates between robotic‐assisted colectomy and laparoscopic colectomy. Favorable perioperative outcomes also suggest the safety and feasibility of robotic‐assisted colectomy.
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spelling pubmed-106239572023-11-04 Robotic‐assisted colectomy for right‐sided colon cancer: Short‐term surgical outcomes of a multi‐institutional prospective cohort study in Japan Yamauchi, Shinichi Shiomi, Akio Matsuda, Chu Takemasa, Ichiro Hanai, Tsunekazu Uemura, Mamoru Kinugasa, Yusuke Ann Gastroenterol Surg Original Articles BACKGROUND: In Japan, there are no substantial reports on robotic‐assisted colectomy because few institutions performed the procedure, as it was not covered by national insurance until March 2022. AIM: This study aimed to evaluate the safety and feasibility of robotic‐assisted colectomy for patients with curatively resectable colon cancer in Japan. METHODS: This multi‐institutional, prospective, single‐arm, observational study enrolled patients diagnosed with curatively resectable clinical stage I–IIIC colon adenocarcinoma with D2 or D3 lymph node dissection and treated with robotic‐assisted colectomy. The primary endpoint was the conversion rate to laparotomy. The non‐inferiority of outcomes for robotic‐assisted colectomy versus laparoscopic colectomy, which was determined from historical data, was verified. RESULTS: One hundred patients were registered between July 2019 and March 2022 and underwent robotic‐assisted colectomy performed by seven expert surgeons at six institutions. Thirteen patients were excluded because their surgeons had insufficient experience performing robotic‐assisted colectomy; therefore, 87 patients were eligible for the primary endpoint analysis. There was no conversion in these 87 patients, and robotic‐assisted colectomy was non‐inferior to laparoscopic colectomy in terms of conversion rate (90% confidence interval 0–3.38, p = 0.0006). No intraoperative adverse events occurred, and no mortality was observed in a total of 100 patients. The rate of patients with Clavien–Dindo complications grade III or higher was 4%. CONCLUSION: This study showed the non‐inferiority of the conversion rates between robotic‐assisted colectomy and laparoscopic colectomy. Favorable perioperative outcomes also suggest the safety and feasibility of robotic‐assisted colectomy. John Wiley and Sons Inc. 2023-05-23 /pmc/articles/PMC10623957/ /pubmed/37927933 http://dx.doi.org/10.1002/ags3.12694 Text en © 2023 The Authors. Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterological Surgery. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Yamauchi, Shinichi
Shiomi, Akio
Matsuda, Chu
Takemasa, Ichiro
Hanai, Tsunekazu
Uemura, Mamoru
Kinugasa, Yusuke
Robotic‐assisted colectomy for right‐sided colon cancer: Short‐term surgical outcomes of a multi‐institutional prospective cohort study in Japan
title Robotic‐assisted colectomy for right‐sided colon cancer: Short‐term surgical outcomes of a multi‐institutional prospective cohort study in Japan
title_full Robotic‐assisted colectomy for right‐sided colon cancer: Short‐term surgical outcomes of a multi‐institutional prospective cohort study in Japan
title_fullStr Robotic‐assisted colectomy for right‐sided colon cancer: Short‐term surgical outcomes of a multi‐institutional prospective cohort study in Japan
title_full_unstemmed Robotic‐assisted colectomy for right‐sided colon cancer: Short‐term surgical outcomes of a multi‐institutional prospective cohort study in Japan
title_short Robotic‐assisted colectomy for right‐sided colon cancer: Short‐term surgical outcomes of a multi‐institutional prospective cohort study in Japan
title_sort robotic‐assisted colectomy for right‐sided colon cancer: short‐term surgical outcomes of a multi‐institutional prospective cohort study in japan
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623957/
https://www.ncbi.nlm.nih.gov/pubmed/37927933
http://dx.doi.org/10.1002/ags3.12694
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