Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis

Factor VII (FVII) is an important, vitamin K-dependent clotting factor. Acquired FVII deficiency is a rare entity that is associated with serious bleeding complications. We report a case of acquired FVII deficiency in a patient with recurrent chronic myeloid leukemia in blast crisis who developed bi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wolf, Emily B., Li, David, Fernandez, Andre J., Gardner, Lindsay B., Rivera, Candido E., Wysokinska, Ewa M., Shaikh, Marwan E., Tun, Han W., Roy, Vivek, Alhaj Moustafa, Muhamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624022/
https://www.ncbi.nlm.nih.gov/pubmed/37919949
http://dx.doi.org/10.1177/23247096231209543
_version_ 1785130850060337152
author Wolf, Emily B.
Li, David
Fernandez, Andre J.
Gardner, Lindsay B.
Rivera, Candido E.
Wysokinska, Ewa M.
Shaikh, Marwan E.
Tun, Han W.
Roy, Vivek
Alhaj Moustafa, Muhamad
author_facet Wolf, Emily B.
Li, David
Fernandez, Andre J.
Gardner, Lindsay B.
Rivera, Candido E.
Wysokinska, Ewa M.
Shaikh, Marwan E.
Tun, Han W.
Roy, Vivek
Alhaj Moustafa, Muhamad
author_sort Wolf, Emily B.
collection PubMed
description Factor VII (FVII) is an important, vitamin K-dependent clotting factor. Acquired FVII deficiency is a rare entity that is associated with serious bleeding complications. We report a case of acquired FVII deficiency in a patient with recurrent chronic myeloid leukemia in blast crisis who developed bilateral retinal hemorrhages. The coagulopathy was corrected with the initiation of chemotherapy and subsequent reduction in peripheral blast count.
format Online
Article
Text
id pubmed-10624022
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-106240222023-11-04 Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis Wolf, Emily B. Li, David Fernandez, Andre J. Gardner, Lindsay B. Rivera, Candido E. Wysokinska, Ewa M. Shaikh, Marwan E. Tun, Han W. Roy, Vivek Alhaj Moustafa, Muhamad J Investig Med High Impact Case Rep Case Report Factor VII (FVII) is an important, vitamin K-dependent clotting factor. Acquired FVII deficiency is a rare entity that is associated with serious bleeding complications. We report a case of acquired FVII deficiency in a patient with recurrent chronic myeloid leukemia in blast crisis who developed bilateral retinal hemorrhages. The coagulopathy was corrected with the initiation of chemotherapy and subsequent reduction in peripheral blast count. SAGE Publications 2023-11-02 /pmc/articles/PMC10624022/ /pubmed/37919949 http://dx.doi.org/10.1177/23247096231209543 Text en © 2023 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Wolf, Emily B.
Li, David
Fernandez, Andre J.
Gardner, Lindsay B.
Rivera, Candido E.
Wysokinska, Ewa M.
Shaikh, Marwan E.
Tun, Han W.
Roy, Vivek
Alhaj Moustafa, Muhamad
Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis
title Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis
title_full Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis
title_fullStr Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis
title_full_unstemmed Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis
title_short Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis
title_sort acquired factor vii deficiency associated with chronic myeloid leukemia blast crisis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624022/
https://www.ncbi.nlm.nih.gov/pubmed/37919949
http://dx.doi.org/10.1177/23247096231209543
work_keys_str_mv AT wolfemilyb acquiredfactorviideficiencyassociatedwithchronicmyeloidleukemiablastcrisis
AT lidavid acquiredfactorviideficiencyassociatedwithchronicmyeloidleukemiablastcrisis
AT fernandezandrej acquiredfactorviideficiencyassociatedwithchronicmyeloidleukemiablastcrisis
AT gardnerlindsayb acquiredfactorviideficiencyassociatedwithchronicmyeloidleukemiablastcrisis
AT riveracandidoe acquiredfactorviideficiencyassociatedwithchronicmyeloidleukemiablastcrisis
AT wysokinskaewam acquiredfactorviideficiencyassociatedwithchronicmyeloidleukemiablastcrisis
AT shaikhmarwane acquiredfactorviideficiencyassociatedwithchronicmyeloidleukemiablastcrisis
AT tunhanw acquiredfactorviideficiencyassociatedwithchronicmyeloidleukemiablastcrisis
AT royvivek acquiredfactorviideficiencyassociatedwithchronicmyeloidleukemiablastcrisis
AT alhajmoustafamuhamad acquiredfactorviideficiencyassociatedwithchronicmyeloidleukemiablastcrisis

Ejemplares similares