Concurrent Occurrence of Neuropsychiatric Systemic Lupus Erythematosus and Sarcoidosis: A Case Report

Systemic lupus erythematosus (SLE) and sarcoidosis are both complex autoimmune disorders with varying clinical manifestations. The incidence of SLE is as low as 4.91 per 100,000 population, and that of sarcoidosis is 0.85 per 100,000 population. The prevalence of neuropsychiatric systemic lupus eryt...

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Autores principales: Kharel, Manish, Parajuli, Bibek, Timilsina, Sunil, Thapa Chhetri, Suchit, Kunwor, Bishal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624149/
https://www.ncbi.nlm.nih.gov/pubmed/37927759
http://dx.doi.org/10.7759/cureus.46464
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author Kharel, Manish
Parajuli, Bibek
Timilsina, Sunil
Thapa Chhetri, Suchit
Kunwor, Bishal
author_facet Kharel, Manish
Parajuli, Bibek
Timilsina, Sunil
Thapa Chhetri, Suchit
Kunwor, Bishal
author_sort Kharel, Manish
collection PubMed
description Systemic lupus erythematosus (SLE) and sarcoidosis are both complex autoimmune disorders with varying clinical manifestations. The incidence of SLE is as low as 4.91 per 100,000 population, and that of sarcoidosis is 0.85 per 100,000 population. The prevalence of neuropsychiatric systemic lupus erythematosus (NPSLE) ranges from 17.6% to 44.5%. The concurrent occurrence of NPSLE and sarcoidosis, although rare, presents diagnostic and management challenges. The clinical picture resulting from the coexistence of NPSLE and sarcoidosis, which share a common immunological picture, is not well defined. This case report discusses a patient with coexisting NPSLE and sarcoidosis, highlighting the intricate interplay between these conditions.
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spelling pubmed-106241492023-11-04 Concurrent Occurrence of Neuropsychiatric Systemic Lupus Erythematosus and Sarcoidosis: A Case Report Kharel, Manish Parajuli, Bibek Timilsina, Sunil Thapa Chhetri, Suchit Kunwor, Bishal Cureus Neurology Systemic lupus erythematosus (SLE) and sarcoidosis are both complex autoimmune disorders with varying clinical manifestations. The incidence of SLE is as low as 4.91 per 100,000 population, and that of sarcoidosis is 0.85 per 100,000 population. The prevalence of neuropsychiatric systemic lupus erythematosus (NPSLE) ranges from 17.6% to 44.5%. The concurrent occurrence of NPSLE and sarcoidosis, although rare, presents diagnostic and management challenges. The clinical picture resulting from the coexistence of NPSLE and sarcoidosis, which share a common immunological picture, is not well defined. This case report discusses a patient with coexisting NPSLE and sarcoidosis, highlighting the intricate interplay between these conditions. Cureus 2023-10-04 /pmc/articles/PMC10624149/ /pubmed/37927759 http://dx.doi.org/10.7759/cureus.46464 Text en Copyright © 2023, Kharel et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Kharel, Manish
Parajuli, Bibek
Timilsina, Sunil
Thapa Chhetri, Suchit
Kunwor, Bishal
Concurrent Occurrence of Neuropsychiatric Systemic Lupus Erythematosus and Sarcoidosis: A Case Report
title Concurrent Occurrence of Neuropsychiatric Systemic Lupus Erythematosus and Sarcoidosis: A Case Report
title_full Concurrent Occurrence of Neuropsychiatric Systemic Lupus Erythematosus and Sarcoidosis: A Case Report
title_fullStr Concurrent Occurrence of Neuropsychiatric Systemic Lupus Erythematosus and Sarcoidosis: A Case Report
title_full_unstemmed Concurrent Occurrence of Neuropsychiatric Systemic Lupus Erythematosus and Sarcoidosis: A Case Report
title_short Concurrent Occurrence of Neuropsychiatric Systemic Lupus Erythematosus and Sarcoidosis: A Case Report
title_sort concurrent occurrence of neuropsychiatric systemic lupus erythematosus and sarcoidosis: a case report
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624149/
https://www.ncbi.nlm.nih.gov/pubmed/37927759
http://dx.doi.org/10.7759/cureus.46464
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