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Stem cell mutations, associated cancer risk, and consequences for regenerative medicine
Mutation accumulation in stem cells has been associated with cancer risk. However, the presence of numerous mutant clones in healthy tissues has raised the question of what limits cancer initiation. Here, we review recent developments in characterizing mutation accumulation in healthy tissues and co...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624213/ https://www.ncbi.nlm.nih.gov/pubmed/37832550 http://dx.doi.org/10.1016/j.stem.2023.09.008 |