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Bioinspired, vertically stacked, and perovskite nanocrystal–enhanced CMOS imaging sensors for resolving UV spectral signatures

Imaging and identifying target signatures and biomedical markers in the ultraviolet (UV) spectrum is broadly important to medical imaging, military target tracking, remote sensing, and industrial automation. However, current silicon-based imaging sensors are fundamentally limited because of the rapi...

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Autores principales: Chen, Cheng, Wang, Ziwen, Wu, Jiajing, Deng, Zhengtao, Zhang, Tao, Zhu, Zhongmin, Jin, Yifei, Lew, Benjamin, Srivastava, Indrajit, Liang, Zuodong, Nie, Shuming, Gruev, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624339/
https://www.ncbi.nlm.nih.gov/pubmed/37922355
http://dx.doi.org/10.1126/sciadv.adk3860
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author Chen, Cheng
Wang, Ziwen
Wu, Jiajing
Deng, Zhengtao
Zhang, Tao
Zhu, Zhongmin
Jin, Yifei
Lew, Benjamin
Srivastava, Indrajit
Liang, Zuodong
Nie, Shuming
Gruev, Viktor
author_facet Chen, Cheng
Wang, Ziwen
Wu, Jiajing
Deng, Zhengtao
Zhang, Tao
Zhu, Zhongmin
Jin, Yifei
Lew, Benjamin
Srivastava, Indrajit
Liang, Zuodong
Nie, Shuming
Gruev, Viktor
author_sort Chen, Cheng
collection PubMed
description Imaging and identifying target signatures and biomedical markers in the ultraviolet (UV) spectrum is broadly important to medical imaging, military target tracking, remote sensing, and industrial automation. However, current silicon-based imaging sensors are fundamentally limited because of the rapid absorption and attenuation of UV light, hindering their ability to resolve UV spectral signatures. Here, we present a bioinspired imaging sensor capable of wavelength-resolved imaging in the UV range. Inspired by the UV-sensitive visual system of the Papilio xuthus butterfly, the sensor monolithically combines vertically stacked photodiodes and perovskite nanocrystals. This imaging design combines two complementary UV detection mechanisms: The nanocrystal layer converts a portion of UV signals into visible fluorescence, detected by the photodiode array, while the remaining UV light is detected by the top photodiode. Our label-free UV fluorescence imaging data from aromatic amino acids and cancer/normal cells enables real-time differentiation of these biomedical materials with 99% confidence.
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spelling pubmed-106243392023-11-04 Bioinspired, vertically stacked, and perovskite nanocrystal–enhanced CMOS imaging sensors for resolving UV spectral signatures Chen, Cheng Wang, Ziwen Wu, Jiajing Deng, Zhengtao Zhang, Tao Zhu, Zhongmin Jin, Yifei Lew, Benjamin Srivastava, Indrajit Liang, Zuodong Nie, Shuming Gruev, Viktor Sci Adv Physical and Materials Sciences Imaging and identifying target signatures and biomedical markers in the ultraviolet (UV) spectrum is broadly important to medical imaging, military target tracking, remote sensing, and industrial automation. However, current silicon-based imaging sensors are fundamentally limited because of the rapid absorption and attenuation of UV light, hindering their ability to resolve UV spectral signatures. Here, we present a bioinspired imaging sensor capable of wavelength-resolved imaging in the UV range. Inspired by the UV-sensitive visual system of the Papilio xuthus butterfly, the sensor monolithically combines vertically stacked photodiodes and perovskite nanocrystals. This imaging design combines two complementary UV detection mechanisms: The nanocrystal layer converts a portion of UV signals into visible fluorescence, detected by the photodiode array, while the remaining UV light is detected by the top photodiode. Our label-free UV fluorescence imaging data from aromatic amino acids and cancer/normal cells enables real-time differentiation of these biomedical materials with 99% confidence. American Association for the Advancement of Science 2023-11-03 /pmc/articles/PMC10624339/ /pubmed/37922355 http://dx.doi.org/10.1126/sciadv.adk3860 Text en Copyright © 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Physical and Materials Sciences
Chen, Cheng
Wang, Ziwen
Wu, Jiajing
Deng, Zhengtao
Zhang, Tao
Zhu, Zhongmin
Jin, Yifei
Lew, Benjamin
Srivastava, Indrajit
Liang, Zuodong
Nie, Shuming
Gruev, Viktor
Bioinspired, vertically stacked, and perovskite nanocrystal–enhanced CMOS imaging sensors for resolving UV spectral signatures
title Bioinspired, vertically stacked, and perovskite nanocrystal–enhanced CMOS imaging sensors for resolving UV spectral signatures
title_full Bioinspired, vertically stacked, and perovskite nanocrystal–enhanced CMOS imaging sensors for resolving UV spectral signatures
title_fullStr Bioinspired, vertically stacked, and perovskite nanocrystal–enhanced CMOS imaging sensors for resolving UV spectral signatures
title_full_unstemmed Bioinspired, vertically stacked, and perovskite nanocrystal–enhanced CMOS imaging sensors for resolving UV spectral signatures
title_short Bioinspired, vertically stacked, and perovskite nanocrystal–enhanced CMOS imaging sensors for resolving UV spectral signatures
title_sort bioinspired, vertically stacked, and perovskite nanocrystal–enhanced cmos imaging sensors for resolving uv spectral signatures
topic Physical and Materials Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624339/
https://www.ncbi.nlm.nih.gov/pubmed/37922355
http://dx.doi.org/10.1126/sciadv.adk3860
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