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Angiopoietin-like 3 inhibition and the liver: less is more?

PURPOSE OF REVIEW: The aim of this study was to discuss the potential mechanisms and implications of the opposing liver safety results from recent angiopoietin-like 3 (ANGPTL3) inhibition studies. RECENT FINDINGS: The clinical development of vupanorsen, a N-acetylgalactosamine (GalNAc) antisense tar...

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Detalles Bibliográficos
Autores principales: Oostveen, Reindert F., Hovingh, G. Kees, Stroes, Erik S.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624415/
https://www.ncbi.nlm.nih.gov/pubmed/37820081
http://dx.doi.org/10.1097/MOL.0000000000000898