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Cellular Heterogeneity of Activated Primary Human Macrophages and Associated Drug–Gene Networks: From Biology to Precision Therapeutics

BACKGROUND: Interferon-γ (IFNγ) signaling plays a complex role in atherogenesis. IFNγ stimulation of macrophages permits in vitro exploration of proinflammatory mechanisms and the development of novel immune therapies. We hypothesized that the study of macrophage subpopulations could lead to anti-in...

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Detalles Bibliográficos
Autores principales:	Decano, Julius L., Maiorino, Enrico, Matamalas, Joan T., Chelvanambi, Sarvesh, Tiemeijer, Bart M., Yanagihara, Yoshihiro, Mukai, Shin, Jha, Prabhash Kumar, Pestana, Diego V.S., D’Souza, Edwin, Whelan, Mary, Ge, Rile, Asano, Takaharu, Sharma, Amitabh, Libby, Peter, Singh, Sasha A., Aikawa, Elena, Aikawa, Masanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624416/ https://www.ncbi.nlm.nih.gov/pubmed/37850387 http://dx.doi.org/10.1161/CIRCULATIONAHA.123.064794

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