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Design of allosteric sites into rotary motor V(1)-ATPase by restoring lost function of pseudo-active sites
Allostery produces concerted functions of protein complexes by orchestrating the cooperative work between the constituent subunits. Here we describe an approach to create artificial allosteric sites in protein complexes. Certain protein complexes contain subunits with pseudo-active sites, which are...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624635/ https://www.ncbi.nlm.nih.gov/pubmed/37414880 http://dx.doi.org/10.1038/s41557-023-01256-4 |