Empagliflozin suppresses hedgehog pathway, alleviates ER stress, and ameliorates hepatic fibrosis in rats

Worldwide mortality from hepatic fibrosis remains high, due to hepatocellular carcinoma and end stage liver failure. The progressive nature of hepatic fibrosis from inflammation to cicatrized tissues warrants subtle intervention with pharmacological agents that hold potential. Empagliflozin (Empa),...

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Detalles Bibliográficos
Autores principales: Abdalla, Nourihan, Abo-ElMatty, Dina M., Saleh, Sami, Ghattas, Maivel H., Omar, Nesreen Nabil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624673/
https://www.ncbi.nlm.nih.gov/pubmed/37923828
http://dx.doi.org/10.1038/s41598-023-46288-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624673/
https://www.ncbi.nlm.nih.gov/pubmed/37923828
http://dx.doi.org/10.1038/s41598-023-46288-5

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