A gut microbial metabolite of linoleic acid ameliorates liver fibrosis by inhibiting TGF-β signaling in hepatic stellate cells

The antidiabetic drug pioglitazone ameliorates insulin resistance by activating the transcription factor PPARγ. In addition to its blood glucose–lowering action, pioglitazone exerts pleiotropic effects including amelioration of nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (N...

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Detalles Bibliográficos
Autores principales: Kasahara, Nanaho, Imi, Yukiko, Amano, Reina, Shinohara, Masakazu, Okada, Kumiko, Hosokawa, Yusei, Imamori, Makoto, Tomimoto, Chiaki, Kunisawa, Jun, Kishino, Shigenobu, Ogawa, Jun, Ogawa, Wataru, Hosooka, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624680/
https://www.ncbi.nlm.nih.gov/pubmed/37923895
http://dx.doi.org/10.1038/s41598-023-46404-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624680/
https://www.ncbi.nlm.nih.gov/pubmed/37923895
http://dx.doi.org/10.1038/s41598-023-46404-5

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