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A gut microbial metabolite of linoleic acid ameliorates liver fibrosis by inhibiting TGF-β signaling in hepatic stellate cells
The antidiabetic drug pioglitazone ameliorates insulin resistance by activating the transcription factor PPARγ. In addition to its blood glucose–lowering action, pioglitazone exerts pleiotropic effects including amelioration of nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (N...
Autores principales: | Kasahara, Nanaho, Imi, Yukiko, Amano, Reina, Shinohara, Masakazu, Okada, Kumiko, Hosokawa, Yusei, Imamori, Makoto, Tomimoto, Chiaki, Kunisawa, Jun, Kishino, Shigenobu, Ogawa, Jun, Ogawa, Wataru, Hosooka, Tetsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624680/ https://www.ncbi.nlm.nih.gov/pubmed/37923895 http://dx.doi.org/10.1038/s41598-023-46404-5 |
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