Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma

Chemo-activation of mitochondrial ClpP exhibits promising anticancer properties. However, we are currently unaware of any studies using selective and potent ClpP activators in lung squamous cell carcinoma. In this work, we report on such an activator, ZK53, which exhibits therapeutic effects on lung...

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Detalles Bibliográficos
Autores principales: Zhou, Lin-Lin, Zhang, Tao, Xue, Yun, Yue, Chuan, Pan, Yihui, Wang, Pengyu, Yang, Teng, Li, Meixia, Zhou, Hu, Ding, Kan, Gan, Jianhua, Ji, Hongbin, Yang, Cai-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624687/
https://www.ncbi.nlm.nih.gov/pubmed/37923710
http://dx.doi.org/10.1038/s41467-023-42784-4

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