Cargando…

Efficacy and safety of polyethylene glycol loxenatide in type 2 diabetic patients: a systematic review and meta-analysis of randomized controlled trials

Polyethylene glycol loxenatide (PEX168) is a novel glucagon-like peptide-1 receptor agonist with a longer half-life developed by modifying the chemical structure of exenatide. This study aims to assess the efficacy and safety of PEX168 and determine the best dose. We searched PubMed, Scopus, Cochran...

Descripción completa

Detalles Bibliográficos
Autores principales:	Salamah, Hazem Mohamed, Marey, Ahmed, Elsayed, Esraa, Hasan, Mohammed Tarek, Mahmoud, Abdelrahman, Abualkhair, Khaled Alsayed, Abo-elnour, Dina Essam, Abdelhaleem, Ibrahim Abdelmonaem, Abd-Elgawad, Mohamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624877/ https://www.ncbi.nlm.nih.gov/pubmed/37923756 http://dx.doi.org/10.1038/s41598-023-46274-x

Ejemplares similares

Polyethylene glycol loxenatide (PEX168) in subjects with renal impairment: A pharmacokinetic study
por: Wang, Jianwen, et al.
Publicado: (2019)

Polyethylene Glycol Loxenatide (PEX-168) Reduces Body Weight and Blood Glucose in Simple Obese Mice
por: Wu, Yuting, et al.
Publicado: (2021)

The efficacy of oxytocin gel in postmenopausal women with vaginal atrophy: an updated systematic review and meta-analysis
por: Farahat, Ramadan Abdelmoez, et al.
Publicado: (2023)

Protective Effects and Mechanisms of Polyethylene Glycol Loxenatide Against Hyperglycemia and Liver Injury in db/db diabetic Mice
por: Zhang, Yu, et al.
Publicado: (2021)

Long-Term Cost-Effectiveness of Subcutaneous Once-Weekly Semaglutide Versus Polyethylene Glycol Loxenatide for Treatment of Type 2 Diabetes Mellitus in China
por: Liu, Lei, et al.
Publicado: (2022)

Efficacy of polyethylene glycol loxenatide versus insulin glargine on glycemic control in patients with type 2 diabetes: a randomized, open-label, parallel-group trial
por: Zhang, Shuo, et al.
Publicado: (2023)

Polyethylene Glycol Loxenatide Injection (GLP-1) Protects Vascular Endothelial Cell Function in Middle-Aged and Elderly Patients With Type 2 Diabetes by Regulating Gut Microbiota
por: Chen, Fengwu, et al.
Publicado: (2022)

Short-term effect of polyethylene glycol loxenatide on weight loss in overweight or obese patients with type 2 diabetes: An open-label, parallel-arm, randomized, metformin-controlled trial
por: Cai, Hongyu, et al.
Publicado: (2023)

Impact of polyethylene glycol loxenatide on cardiovascular outcomes in patients with type 2 diabetes: study protocol for a multicentre, randomised, double-blind, placebo-controlled trial (BALANCE-3)
por: Xie, Yun, et al.
Publicado: (2023)

Synthesis and Characterization of Polyethylene Glycol-Grafted Photoreactive Polyethylene Glycols for Antibiofouling Applications
por: Othman, Mahmoud H., et al.
Publicado: (2022)

Bactericidal activity of propylene glycol, glycerine, polyethylene glycol 400, and polyethylene glycol 1000 against selected microorganisms
por: Nalawade, Triveni Mohan, et al.
Publicado: (2015)

Synthesis of Stable Cholesteryl–Polyethylene Glycol–Peptide Conjugates with Non-Disperse Polyethylene Glycol Lengths
por: Cristóbal-Lecina, Edgar, et al.
Publicado: (2020)

Polyethylene Glycol 3350 With Electrolytes Versus Polyethylene Glycol 4000 for Constipation: A Randomized, Controlled Trial
por: Bekkali, Noor L.H., et al.
Publicado: (2018)

The Potential of Polyethylene Terephthalate Glycol as Biomaterial for Bone Tissue Engineering
por: Hassan, Mohamed H., et al.
Publicado: (2020)

Polyethylene glycol as a cause of anaphylaxis
por: Wylon, Katharina, et al.
Publicado: (2016)

Polyethylene Glycol Camouflaged Earthworm Hemoglobin
por: Jani, Vivek P., et al.
Publicado: (2017)

Effects of polyethylene glycol content on the properties of a silk fibroin/nano-hydroxyapatite/polyethylene glycol electrospun scaffold
por: Qi, Qi, et al.
Publicado: (2019)

On the Behavior of the Ethylene Glycol Components of Polydisperse Polyethylene Glycol PEG200
por: Hoffmann, Markus M., et al.
Publicado: (2023)

Interaction of polyethylene glycol with cytochrome c investigated via in vitro and in silico approaches
por: Parray, Zahoor Ahmad, et al.
Publicado: (2021)

The application of polyethylene glycol (PEG) to electron microscopy
Publicado: (1980)

Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates
por: Pyreddy, Suneela, et al.
Publicado: (2014)

Anaphylactic Shock Caused by Ingestion of Polyethylene Glycol
por: Lee, Sun Hee, et al.
Publicado: (2015)

Polyethylene Glycol for Small Bowel Capsule Endoscopy
por: Yang, Li, et al.
Publicado: (2017)

Effect of Polyethylene Glycol on the NiO Photocathode
por: Li, Shengjun, et al.
Publicado: (2017)

Structural basis of polyethylene glycol recognition by antibody
por: Lee, Cheng-Chung, et al.
Publicado: (2020)

Iso-osmolar hyponatremia from polyethylene glycol
por: Tucker, Bryan M, et al.
Publicado: (2020)

Permeation of polyethylene glycols across the tympanic membrane
por: Zhang, Wei, et al.
Publicado: (2021)

Intrusion of polyethylene glycol into solid-state nanopores
por: Sun, Yueting, et al.
Publicado: (2018)

Hypersensitivity to different polyethylene glycol–containing products
por: Khalid, Muhammad Bilal, et al.
Publicado: (2021)

Polyethylene Glycol 20k. Does It Fluoresce?
por: Laatsch, Bethany F., et al.
Publicado: (2023)

Polyethylene Glycol Preconditioning: An Effective Strategy to Prevent Liver Ischemia Reperfusion Injury
por: Bejaoui, Mohamed, et al.
Publicado: (2016)

Low volume polyethylene glycol combined with senna versus high volume polyethylene glycol, which regimen is better for bowel preparation for colonoscopy? A randomized, controlled, and single‐blinded trial
por: Sadeghi, Amir, et al.
Publicado: (2022)

Polyethylene Glycol-Mediated Directional Conjugation of Biological Molecules for Enhanced Immunoassays at the Point-of-Care
por: Battalapalli, Dheerendranath, et al.
Publicado: (2023)

Polyethylene glycol and bisacodyl for colonoscopy: has the time arrived?
por: Hassan, Cesare, et al.
Publicado: (2013)

Anaphylaxis to Polyethylene Glycol (Colyte®) in a Patient with Diverticulitis
por: Lee, So-Hee, et al.
Publicado: (2016)

Photodynamic Effect of Polyethylene Glycol–modified Fullerene on Tumor
por: Tabata, Yasuhiko, et al.
Publicado: (1997)

Relaxation Dynamics in Polyethylene Glycol/Modified Hydrotalcite Nanocomposites
por: Arrigo, Rossella, et al.
Publicado: (2018)

Simplified Transformation of Ostreococcus tauri Using Polyethylene Glycol
por: Sanchez, Frédéric, et al.
Publicado: (2019)

Relationship between permeability and diffusivity in polyethylene glycol hydrogels
por: Offeddu, G. S., et al.
Publicado: (2018)

Preparation and Characterization of Modified Soda Lignin with Polyethylene Glycol
por: Zhang, Fangda, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_krjnlarm3veonobqgst505hct9