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Conformational dynamics of α-synuclein and study of its intramolecular forces in the presence of selected compounds

Protein misfolding and aggregation play crucial roles in amyloidogenic diseases through the self-assembly of intrinsically disordered proteins (IDPs) in type II diabetes (T2D), Alzheimer's disease (AD) and Parkinson’s disease (PD). PD is the most common neurodegenerative disorder after AD, and...

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Detalles Bibliográficos
Autores principales:	Khatooni, Zahed, Akhtari, Keivan, Wilson, Heather L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624887/ https://www.ncbi.nlm.nih.gov/pubmed/37923923 http://dx.doi.org/10.1038/s41598-023-46181-1

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