Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy

Regulation of alternative splicing (AS) enables a single transcript to yield multiple isoforms that increase transcriptome and proteome diversity. Here, we report that spliceosome component Usp39 plays a role in the regulation of hepatocyte lipid homeostasis. We demonstrate that Usp39 expression is...

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Detalles Bibliográficos
Autores principales: Cui, Donghai, Wang, Zixiang, Dang, Qianli, Wang, Jing, Qin, Junchao, Song, Jianping, Zhai, Xiangyu, Zhou, Yachao, Zhao, Ling, Lu, Gang, Liu, Hongbin, Liu, Gang, Liu, Runping, Shao, Changshun, Zhang, Xiyu, Liu, Zhaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624899/
https://www.ncbi.nlm.nih.gov/pubmed/37923718
http://dx.doi.org/10.1038/s41467-023-42461-6

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