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An Asymptomatic Patient with Colonic Leiomyoma
Subepithelial lesions (SELs) originating from muscularis mucosae of the colon are very rare findings on endoscopy. Appropriate management of SELs involves making a correct diagnosis and estimating their malignant potential. In this case study, a 58-year-old Saudi man presented with a small, 8-mm sig...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624942/ https://www.ncbi.nlm.nih.gov/pubmed/37928970 http://dx.doi.org/10.1159/000533550 |
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author | Alkhowaiter, Saad Alsheikh, Abdulmalik Alotaibi, Ammar |
author_facet | Alkhowaiter, Saad Alsheikh, Abdulmalik Alotaibi, Ammar |
author_sort | Alkhowaiter, Saad |
collection | PubMed |
description | Subepithelial lesions (SELs) originating from muscularis mucosae of the colon are very rare findings on endoscopy. Appropriate management of SELs involves making a correct diagnosis and estimating their malignant potential. In this case study, a 58-year-old Saudi man presented with a small, 8-mm sigmoid polyp during screening colonoscopy. The polyp was removed by hot snare polypectomy and sent to pathology laboratory. Report showed an unremarkable colonic mucosa and underlying well-circumscribed submucosal lesion composed of monotonous spindle cells. Immunohistochemical (IHC) analysis ruled out CD117-/DOG1-positive GIST and confirmed the lesion as leiomyomatous polyp. Colonic leiomyomas are usually benign and often asymptomatic and discovered during CRC screening procedures. Diagnosis is made on histology/IHC analysis since endoscopically they might be indistinguishable from other SELs. Conventional polypectomy is an appropriate treatment for small colonic leiomyoma and these benign lesions typically do not recur. |
format | Online Article Text |
id | pubmed-10624942 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-106249422023-11-05 An Asymptomatic Patient with Colonic Leiomyoma Alkhowaiter, Saad Alsheikh, Abdulmalik Alotaibi, Ammar Case Rep Gastroenterol Single Case Subepithelial lesions (SELs) originating from muscularis mucosae of the colon are very rare findings on endoscopy. Appropriate management of SELs involves making a correct diagnosis and estimating their malignant potential. In this case study, a 58-year-old Saudi man presented with a small, 8-mm sigmoid polyp during screening colonoscopy. The polyp was removed by hot snare polypectomy and sent to pathology laboratory. Report showed an unremarkable colonic mucosa and underlying well-circumscribed submucosal lesion composed of monotonous spindle cells. Immunohistochemical (IHC) analysis ruled out CD117-/DOG1-positive GIST and confirmed the lesion as leiomyomatous polyp. Colonic leiomyomas are usually benign and often asymptomatic and discovered during CRC screening procedures. Diagnosis is made on histology/IHC analysis since endoscopically they might be indistinguishable from other SELs. Conventional polypectomy is an appropriate treatment for small colonic leiomyoma and these benign lesions typically do not recur. S. Karger AG 2023-09-12 /pmc/articles/PMC10624942/ /pubmed/37928970 http://dx.doi.org/10.1159/000533550 Text en © 2023 The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Single Case Alkhowaiter, Saad Alsheikh, Abdulmalik Alotaibi, Ammar An Asymptomatic Patient with Colonic Leiomyoma |
title | An Asymptomatic Patient with Colonic Leiomyoma |
title_full | An Asymptomatic Patient with Colonic Leiomyoma |
title_fullStr | An Asymptomatic Patient with Colonic Leiomyoma |
title_full_unstemmed | An Asymptomatic Patient with Colonic Leiomyoma |
title_short | An Asymptomatic Patient with Colonic Leiomyoma |
title_sort | asymptomatic patient with colonic leiomyoma |
topic | Single Case |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624942/ https://www.ncbi.nlm.nih.gov/pubmed/37928970 http://dx.doi.org/10.1159/000533550 |
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