Clostridium difficile Bacteremia as a Rare Presentation of Polymicrobial Pyogenic Liver Abscesses and Its Management Challenges

Extracolonic manifestations of Clostridium difficile have been rarely reported. We herein report a case of a 60-year-old immunocompetent man presenting with fever, nausea, abdominal pain, and loose stools for 2 weeks. Triple-phase liver computed tomography demonstrated pyogenic liver abscesses and p...

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Autores principales: Lim, Junghyun, Zaw, Catherine, Abramson, Simon, Lichtenberger, Paola N., John, Binu V., Cuebas-Rosado, Lorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624945/
https://www.ncbi.nlm.nih.gov/pubmed/37928967
http://dx.doi.org/10.1159/000531892
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author Lim, Junghyun
Zaw, Catherine
Abramson, Simon
Lichtenberger, Paola N.
John, Binu V.
Cuebas-Rosado, Lorena
author_facet Lim, Junghyun
Zaw, Catherine
Abramson, Simon
Lichtenberger, Paola N.
John, Binu V.
Cuebas-Rosado, Lorena
author_sort Lim, Junghyun
collection PubMed
description Extracolonic manifestations of Clostridium difficile have been rarely reported. We herein report a case of a 60-year-old immunocompetent man presenting with fever, nausea, abdominal pain, and loose stools for 2 weeks. Triple-phase liver computed tomography demonstrated pyogenic liver abscesses and portal pylephlebitis. Blood cultures grew C. difficile and Bacteroides fragilis, and liver abscess cultures grew Proteus mirabilis, Escherichia coli, and the viridans group Streptococci. Antibiotics coverage was selected to direct at all identified organisms. This demonstrates an unusual case of C. difficile bacteremia in a patient with polymicrobial pyogenic liver abscesses and pylephlebitis.
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spelling pubmed-106249452023-11-05 Clostridium difficile Bacteremia as a Rare Presentation of Polymicrobial Pyogenic Liver Abscesses and Its Management Challenges Lim, Junghyun Zaw, Catherine Abramson, Simon Lichtenberger, Paola N. John, Binu V. Cuebas-Rosado, Lorena Case Rep Gastroenterol Case Report Extracolonic manifestations of Clostridium difficile have been rarely reported. We herein report a case of a 60-year-old immunocompetent man presenting with fever, nausea, abdominal pain, and loose stools for 2 weeks. Triple-phase liver computed tomography demonstrated pyogenic liver abscesses and portal pylephlebitis. Blood cultures grew C. difficile and Bacteroides fragilis, and liver abscess cultures grew Proteus mirabilis, Escherichia coli, and the viridans group Streptococci. Antibiotics coverage was selected to direct at all identified organisms. This demonstrates an unusual case of C. difficile bacteremia in a patient with polymicrobial pyogenic liver abscesses and pylephlebitis. S. Karger AG 2023-09-06 /pmc/articles/PMC10624945/ /pubmed/37928967 http://dx.doi.org/10.1159/000531892 Text en © 2023 The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Lim, Junghyun
Zaw, Catherine
Abramson, Simon
Lichtenberger, Paola N.
John, Binu V.
Cuebas-Rosado, Lorena
Clostridium difficile Bacteremia as a Rare Presentation of Polymicrobial Pyogenic Liver Abscesses and Its Management Challenges
title Clostridium difficile Bacteremia as a Rare Presentation of Polymicrobial Pyogenic Liver Abscesses and Its Management Challenges
title_full Clostridium difficile Bacteremia as a Rare Presentation of Polymicrobial Pyogenic Liver Abscesses and Its Management Challenges
title_fullStr Clostridium difficile Bacteremia as a Rare Presentation of Polymicrobial Pyogenic Liver Abscesses and Its Management Challenges
title_full_unstemmed Clostridium difficile Bacteremia as a Rare Presentation of Polymicrobial Pyogenic Liver Abscesses and Its Management Challenges
title_short Clostridium difficile Bacteremia as a Rare Presentation of Polymicrobial Pyogenic Liver Abscesses and Its Management Challenges
title_sort clostridium difficile bacteremia as a rare presentation of polymicrobial pyogenic liver abscesses and its management challenges
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624945/
https://www.ncbi.nlm.nih.gov/pubmed/37928967
http://dx.doi.org/10.1159/000531892
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