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Red Light‐Triggered Anti‐Angiogenic and Photodynamic Combination Therapy of Age‐Related Macular Degeneration (Adv. Sci. 31/2023)
Red Light‐Activated Combination Therapy of Eye Diseases In article number 2301985, Xiaoling Liang, Weiping Wang, and co‐workers report a red‐light‐triggered intraocular drug release strategy to achieve combination treatment of wet age‐related macular degeneration. Intravenous administration of a pho...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625050/ http://dx.doi.org/10.1002/advs.202370211 |
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author | Xu, Shuting Cui, Kaixuan Long, Kaiqi Li, Jia Fan, Ni Lam, Wai‐Ching Liang, Xiaoling Wang, Weiping |
author_facet | Xu, Shuting Cui, Kaixuan Long, Kaiqi Li, Jia Fan, Ni Lam, Wai‐Ching Liang, Xiaoling Wang, Weiping |
author_sort | Xu, Shuting |
collection | PubMed |
description | Red Light‐Activated Combination Therapy of Eye Diseases In article number 2301985, Xiaoling Liang, Weiping Wang, and co‐workers report a red‐light‐triggered intraocular drug release strategy to achieve combination treatment of wet age‐related macular degeneration. Intravenous administration of a photoactivatable nanosystem followed by light irradiation to the diseased eye leads to intraocular release of an anti‐angiogenic agent, together with selective neo‐vessels occlusion by photodynamic therapy. This study provides a promising paradigm for minimally invasive administration of combination therapeutic agents for angiogenic eye diseases. [Image: see text] |
format | Online Article Text |
id | pubmed-10625050 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-106250502023-11-05 Red Light‐Triggered Anti‐Angiogenic and Photodynamic Combination Therapy of Age‐Related Macular Degeneration (Adv. Sci. 31/2023) Xu, Shuting Cui, Kaixuan Long, Kaiqi Li, Jia Fan, Ni Lam, Wai‐Ching Liang, Xiaoling Wang, Weiping Adv Sci (Weinh) Inside Front Cover Red Light‐Activated Combination Therapy of Eye Diseases In article number 2301985, Xiaoling Liang, Weiping Wang, and co‐workers report a red‐light‐triggered intraocular drug release strategy to achieve combination treatment of wet age‐related macular degeneration. Intravenous administration of a photoactivatable nanosystem followed by light irradiation to the diseased eye leads to intraocular release of an anti‐angiogenic agent, together with selective neo‐vessels occlusion by photodynamic therapy. This study provides a promising paradigm for minimally invasive administration of combination therapeutic agents for angiogenic eye diseases. [Image: see text] John Wiley and Sons Inc. 2023-11-04 /pmc/articles/PMC10625050/ http://dx.doi.org/10.1002/advs.202370211 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Inside Front Cover Xu, Shuting Cui, Kaixuan Long, Kaiqi Li, Jia Fan, Ni Lam, Wai‐Ching Liang, Xiaoling Wang, Weiping Red Light‐Triggered Anti‐Angiogenic and Photodynamic Combination Therapy of Age‐Related Macular Degeneration (Adv. Sci. 31/2023) |
title | Red Light‐Triggered Anti‐Angiogenic and Photodynamic Combination Therapy of Age‐Related Macular Degeneration (Adv. Sci. 31/2023) |
title_full | Red Light‐Triggered Anti‐Angiogenic and Photodynamic Combination Therapy of Age‐Related Macular Degeneration (Adv. Sci. 31/2023) |
title_fullStr | Red Light‐Triggered Anti‐Angiogenic and Photodynamic Combination Therapy of Age‐Related Macular Degeneration (Adv. Sci. 31/2023) |
title_full_unstemmed | Red Light‐Triggered Anti‐Angiogenic and Photodynamic Combination Therapy of Age‐Related Macular Degeneration (Adv. Sci. 31/2023) |
title_short | Red Light‐Triggered Anti‐Angiogenic and Photodynamic Combination Therapy of Age‐Related Macular Degeneration (Adv. Sci. 31/2023) |
title_sort | red light‐triggered anti‐angiogenic and photodynamic combination therapy of age‐related macular degeneration (adv. sci. 31/2023) |
topic | Inside Front Cover |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625050/ http://dx.doi.org/10.1002/advs.202370211 |
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