A Specific Mini‐Intrabody Mediates Lysosome Degradation of Mutant Huntingtin (Adv. Sci. 31/2023)

Lysosome In article number 2301120, Xiao‐Jiang Li, Sen Yan, Shihua Li, and their colleagues utilized a small intrabody peptide linked to lysosomes to effectively reduce mutant proteins, offering a novel approach for the treatment of neurodegenerative diseases. The cover image depicts a rocket, with...

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Detalles Bibliográficos
Autores principales: Li, Caijuan, Lin, Yingqi, Chen, Yizhi, Song, Xichen, Zheng, Xiao, Li, Jiawei, He, Jun, Chen, Xiusheng, Huang, Chunhui, Wang, Wei, Wu, Jianhao, Wu, Jiaxi, Gao, Jiale, Tu, Zhuchi, Li, Xiao‐Jiang, Yan, Sen, Li, Shihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625084/
http://dx.doi.org/10.1002/advs.202370210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625084/
http://dx.doi.org/10.1002/advs.202370210

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