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A Specific Mini‐Intrabody Mediates Lysosome Degradation of Mutant Huntingtin (Adv. Sci. 31/2023)
Lysosome In article number 2301120, Xiao‐Jiang Li, Sen Yan, Shihua Li, and their colleagues utilized a small intrabody peptide linked to lysosomes to effectively reduce mutant proteins, offering a novel approach for the treatment of neurodegenerative diseases. The cover image depicts a rocket, with...
Autores principales: | Li, Caijuan, Lin, Yingqi, Chen, Yizhi, Song, Xichen, Zheng, Xiao, Li, Jiawei, He, Jun, Chen, Xiusheng, Huang, Chunhui, Wang, Wei, Wu, Jianhao, Wu, Jiaxi, Gao, Jiale, Tu, Zhuchi, Li, Xiao‐Jiang, Yan, Sen, Li, Shihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625084/ http://dx.doi.org/10.1002/advs.202370210 |
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