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Rotation of the c‐Ring Promotes the Curvature Sorting of Monomeric ATP Synthases (Adv. Sci. 31/2023)

Monomeric ATP Synthases Monomeric ATP synthases exhibit a preference for curved lipid filaments. The curvature‐seeking behavior relies on the membrane‐mediated attractive interaction between rotating ATP synthases. As a result, conic‐like transient dimers produce a dynamic coupling between protein s...

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Detalles Bibliográficos
Autores principales: Valdivieso González, David, Makowski, Marcin, Lillo, M. Pilar, Cao‐García, Francisco J., Melo, Manuel N., Almendro‐Vedia, Víctor G., López‐Montero, Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625085/
http://dx.doi.org/10.1002/advs.202370213
Descripción
Sumario:Monomeric ATP Synthases Monomeric ATP synthases exhibit a preference for curved lipid filaments. The curvature‐seeking behavior relies on the membrane‐mediated attractive interaction between rotating ATP synthases. As a result, conic‐like transient dimers produce a dynamic coupling between protein shape and membrane curvature. The observed active curvature sorting suggests a new role for the rotational movement ATP synthases and their dynamic self‐assembly. More details can be found in article number 2301606 by Víctor G. Almendro‐Vedia, Iván López‐Montero, and co‐workers. [Image: see text]