Endothelial Cell‐Derived Lactate Triggers Bone Mesenchymal Stem Cell Histone Lactylation to Attenuate Osteoporosis

Blood vessels play a role in osteogenesis and osteoporosis; however, the role of vascular metabolism in these processes remains unclear. The present study finds that ovariectomized mice exhibit reduced blood vessel density in the bone and reduced expression of the endothelial glycolytic regulator py...

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Detalles Bibliográficos
Autores principales: Wu, Jinhui, Hu, Miao, Jiang, Heng, Ma, Jun, Xie, Chong, Zhang, Zheng, Zhou, Xin, Zhao, Jianquan, Tao, Zhengbo, Meng, Yichen, Cai, Zhuyun, Song, Tengfei, Zhang, Chenglin, Gao, Rui, Cai, Chang, Song, Hongyuan, Gao, Yang, Lin, Tao, Wang, Ce, Zhou, Xuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625121/
https://www.ncbi.nlm.nih.gov/pubmed/37752768
http://dx.doi.org/10.1002/advs.202301300

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