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A Case Report of Steroid-Induced Angioedema and Urticaria
Physicians regularly use corticosteroids to treat various conditions, attributing their anti-inflammatory and immunosuppressive properties. Cases of allergic sensitivity reactions and dermatitis induced by corticosteroids are relatively uncommon. We present a case regarding an 81-year-old male with...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625174/ https://www.ncbi.nlm.nih.gov/pubmed/37927648 http://dx.doi.org/10.7759/cureus.46515 |
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author | Wan, Leo Thomas, John Yan, Audrey Mann, Jake Szema, Anthony |
author_facet | Wan, Leo Thomas, John Yan, Audrey Mann, Jake Szema, Anthony |
author_sort | Wan, Leo |
collection | PubMed |
description | Physicians regularly use corticosteroids to treat various conditions, attributing their anti-inflammatory and immunosuppressive properties. Cases of allergic sensitivity reactions and dermatitis induced by corticosteroids are relatively uncommon. We present a case regarding an 81-year-old male with a history of actinic keratosis, atopic dermatitis, and psoriasis, who experienced a Type I hypersensitivity reaction with facial angioedema and urticaria on his axilla, torso, and popliteal fossa that developed after treatment with oral prednisolone. This episode also exacerbated his previously diagnosed psoriasis. To treat psoriasis, a dermatologist prescribed clobetasol topical ointment, which did not alleviate the symptoms; instead, it only exacerbated the rash, and he was subsequently referred for corticosteroid allergy testing. North American 85 Comprehensive Series patch testing revealed a positive test for various classes of steroids, including clobetasol-17-propionate, budesonide, and dexamethasone, thus proving a T cell-mediated allergy to corticosteroids. |
format | Online Article Text |
id | pubmed-10625174 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-106251742023-11-05 A Case Report of Steroid-Induced Angioedema and Urticaria Wan, Leo Thomas, John Yan, Audrey Mann, Jake Szema, Anthony Cureus Dermatology Physicians regularly use corticosteroids to treat various conditions, attributing their anti-inflammatory and immunosuppressive properties. Cases of allergic sensitivity reactions and dermatitis induced by corticosteroids are relatively uncommon. We present a case regarding an 81-year-old male with a history of actinic keratosis, atopic dermatitis, and psoriasis, who experienced a Type I hypersensitivity reaction with facial angioedema and urticaria on his axilla, torso, and popliteal fossa that developed after treatment with oral prednisolone. This episode also exacerbated his previously diagnosed psoriasis. To treat psoriasis, a dermatologist prescribed clobetasol topical ointment, which did not alleviate the symptoms; instead, it only exacerbated the rash, and he was subsequently referred for corticosteroid allergy testing. North American 85 Comprehensive Series patch testing revealed a positive test for various classes of steroids, including clobetasol-17-propionate, budesonide, and dexamethasone, thus proving a T cell-mediated allergy to corticosteroids. Cureus 2023-10-05 /pmc/articles/PMC10625174/ /pubmed/37927648 http://dx.doi.org/10.7759/cureus.46515 Text en Copyright © 2023, Wan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Dermatology Wan, Leo Thomas, John Yan, Audrey Mann, Jake Szema, Anthony A Case Report of Steroid-Induced Angioedema and Urticaria |
title | A Case Report of Steroid-Induced Angioedema and Urticaria |
title_full | A Case Report of Steroid-Induced Angioedema and Urticaria |
title_fullStr | A Case Report of Steroid-Induced Angioedema and Urticaria |
title_full_unstemmed | A Case Report of Steroid-Induced Angioedema and Urticaria |
title_short | A Case Report of Steroid-Induced Angioedema and Urticaria |
title_sort | case report of steroid-induced angioedema and urticaria |
topic | Dermatology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625174/ https://www.ncbi.nlm.nih.gov/pubmed/37927648 http://dx.doi.org/10.7759/cureus.46515 |
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