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The Streptococcus virulence protein PepO triggers anti-tumor immune responses by reprograming tumor-associated macrophages in a mouse triple negative breast cancer model

BACKGROUND: The efficacy of current surgery and chemotherapy for triple negative breast cancer (TNBC) is limited due to heterogenous and immunosuppressive tumor microenvironment (TME). Tumor associated macrophages (TAMs), which are regarded as an M2 tumor-promoting phenotype, are crucial in the deve...

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Detalles Bibliográficos
Autores principales:	Liu, Bichen, Huang, Jun, Xiao, Jiangming, Xu, Wenlong, Zhang, Hong, Yuan, Yuan, Yin, Yibing, Zhang, Xuemei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625220/ https://www.ncbi.nlm.nih.gov/pubmed/37925462 http://dx.doi.org/10.1186/s13578-023-01153-w

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