Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs

Alternative lengthening of telomeres (ALT) is a telomere maintenance mechanism activated in ~10–15% of cancers, characterized by telomeric damage. Telomeric damage-induced long non-coding RNAs (dilncRNAs) are transcribed at dysfunctional telomeres and contribute to telomeric DNA damage response (DDR...

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Detalles Bibliográficos
Autores principales: Rosso, Ilaria, Jones-Weinert, Corey, Rossiello, Francesca, Cabrini, Matteo, Brambillasca, Silvia, Munoz-Sagredo, Leonel, Lavagnino, Zeno, Martini, Emanuele, Tedone, Enzo, Garre’, Massimiliano, Aguado, Julio, Parazzoli, Dario, Mione, Marina, Shay, Jerry W., Mercurio, Ciro, d’Adda di Fagagna, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625592/
https://www.ncbi.nlm.nih.gov/pubmed/37925537
http://dx.doi.org/10.1038/s41467-023-42831-0

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