Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function

Biosynthesis drives the cell volume increase during T cell activation. However, the contribution of cell volume regulation in TCR signaling during T lymphoblast formation and its underlying mechanisms remain unclear. Here we show that cell volume regulation is required for optimal T cell activation....

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Detalles Bibliográficos
Autores principales: Wang, Yuman, Sun, Zaiqiao, Ping, Jieming, Tang, Jianlong, He, Boxiao, Chang, Teding, Zhou, Qian, Yuan, Shijie, Tang, Zhaohui, Li, Xin, Lu, Yan, He, Ran, He, Ximiao, Liu, Zheng, Yin, Lei, Wu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625614/
https://www.ncbi.nlm.nih.gov/pubmed/37925509
http://dx.doi.org/10.1038/s41467-023-42817-y

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