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SUMOylation-triggered ALIX activation modulates extracellular vesicles circTLCD4-RWDD3 to promote lymphatic metastasis of non-small cell lung cancer

Lymph node (LN) metastasis is one of the predominant metastatic routes of non-small cell lung cancer (NSCLC) and is considered as a leading cause for the unsatisfactory prognosis of patients. Although lymphangiogenesis is well-recognized as a crucial process in mediating LN metastasis, the regulator...

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Detalles Bibliográficos
Autores principales: Diao, Xiayao, Guo, Chao, Zheng, Hanhao, Zhao, Ke, Luo, Yuming, An, Mingjie, Lin, Yan, Chen, Jiancheng, Li, Yuanlong, Li, Yuting, Gao, Xuehan, Zhang, Jiaqi, Zhou, Mengxin, Bai, Wenliang, Liu, Lei, Wang, Guige, Zhang, Lanjun, He, Xiaotian, Zhang, Rusi, Li, Zhihua, Chen, Changhao, Li, Shanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625632/
https://www.ncbi.nlm.nih.gov/pubmed/37925421
http://dx.doi.org/10.1038/s41392-023-01685-0