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Bullous Lichen Planus of the Nails: A Case Report and Review of the Literature

Lichen planus is a chronic inflammatory disorder that may affect the skin, nails, and/or oral mucosa. Bullous lichen planus is a rare variant of lichen planus, which is even less common in the nails. We present a case of nail bullous lichen planus, in a 48-year-old male presenting with a 10-month hi...

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Autores principales: Hwang, Jonathan K., Magro, Cynthia M., Lipner, Shari R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625817/
https://www.ncbi.nlm.nih.gov/pubmed/37933228
http://dx.doi.org/10.1159/000533386
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author Hwang, Jonathan K.
Magro, Cynthia M.
Lipner, Shari R.
author_facet Hwang, Jonathan K.
Magro, Cynthia M.
Lipner, Shari R.
author_sort Hwang, Jonathan K.
collection PubMed
description Lichen planus is a chronic inflammatory disorder that may affect the skin, nails, and/or oral mucosa. Bullous lichen planus is a rare variant of lichen planus, which is even less common in the nails. We present a case of nail bullous lichen planus, in a 48-year-old male presenting with a 10-month history of onychodystrophy of all ten fingernails. A longitudinal excision of the left thumbnail was performed, with histopathology consistent with lichen planus with focal transition to bullous lichen planus. He was treated with intralesional triamcinolone injections to the fingernails monthly, with improvements noted after three treatments. Our patient’s nail bullous lichen planus manifested with longitudinal ridging, white-yellow discoloration, onycholysis, subungual hyperkeratosis, and v-shaped nicking. Histopathological findings included classical lichen planus changes, as well as formation of subepidermal bullae, colloid bodies, and extensive inflammatory infiltrate. Increased awareness and high index of suspicion for this condition are necessary, given the often late diagnosis reported in previously published cases.
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spelling pubmed-106258172023-11-06 Bullous Lichen Planus of the Nails: A Case Report and Review of the Literature Hwang, Jonathan K. Magro, Cynthia M. Lipner, Shari R. Case Rep Dermatol Single Case Lichen planus is a chronic inflammatory disorder that may affect the skin, nails, and/or oral mucosa. Bullous lichen planus is a rare variant of lichen planus, which is even less common in the nails. We present a case of nail bullous lichen planus, in a 48-year-old male presenting with a 10-month history of onychodystrophy of all ten fingernails. A longitudinal excision of the left thumbnail was performed, with histopathology consistent with lichen planus with focal transition to bullous lichen planus. He was treated with intralesional triamcinolone injections to the fingernails monthly, with improvements noted after three treatments. Our patient’s nail bullous lichen planus manifested with longitudinal ridging, white-yellow discoloration, onycholysis, subungual hyperkeratosis, and v-shaped nicking. Histopathological findings included classical lichen planus changes, as well as formation of subepidermal bullae, colloid bodies, and extensive inflammatory infiltrate. Increased awareness and high index of suspicion for this condition are necessary, given the often late diagnosis reported in previously published cases. S. Karger AG 2023-09-04 /pmc/articles/PMC10625817/ /pubmed/37933228 http://dx.doi.org/10.1159/000533386 Text en © 2023 The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Hwang, Jonathan K.
Magro, Cynthia M.
Lipner, Shari R.
Bullous Lichen Planus of the Nails: A Case Report and Review of the Literature
title Bullous Lichen Planus of the Nails: A Case Report and Review of the Literature
title_full Bullous Lichen Planus of the Nails: A Case Report and Review of the Literature
title_fullStr Bullous Lichen Planus of the Nails: A Case Report and Review of the Literature
title_full_unstemmed Bullous Lichen Planus of the Nails: A Case Report and Review of the Literature
title_short Bullous Lichen Planus of the Nails: A Case Report and Review of the Literature
title_sort bullous lichen planus of the nails: a case report and review of the literature
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625817/
https://www.ncbi.nlm.nih.gov/pubmed/37933228
http://dx.doi.org/10.1159/000533386
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