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Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2

Oxidized albumin (oxHSA) is elevated in several pathological conditions, such as decompensated cirrhosis, acute on chronic liver failure and liver mediated renal failure. Patient derived oxidized albumin was previously shown to be an inflammatory mediator, and in normal serum levels of oxHSA are low...

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Detalles Bibliográficos
Autores principales: Holte, Christopher, Szafranska, Karolina, Kruse, Larissa, Simon-Santamaria, Jaione, Li, Ruomei, Svistounov, Dmitri, McCourt, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625979/
https://www.ncbi.nlm.nih.gov/pubmed/37926735
http://dx.doi.org/10.1038/s41598-023-46462-9