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Bromodomain and extraterminal (BET) proteins: biological functions, diseases, and targeted therapy

BET proteins, which influence gene expression and contribute to the development of cancer, are epigenetic interpreters. Thus, BET inhibitors represent a novel form of epigenetic anticancer treatment. Although preliminary clinical trials have shown the anticancer potential of BET inhibitors, it appea...

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Detalles Bibliográficos
Autores principales: Wang, Zhi-Qiang, Zhang, Zhao-Cong, Wu, Yu-Yang, Pi, Ya-Nan, Lou, Sheng-Han, Liu, Tian-Bo, Lou, Ge, Yang, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625992/
https://www.ncbi.nlm.nih.gov/pubmed/37926722
http://dx.doi.org/10.1038/s41392-023-01647-6