Design, synthesis and antiproliferative screening of newly synthesized coumarin-acrylamide hybrids as potential cytotoxic and apoptosis inducing agents

On the basis of the observed biological activity of coumarin and acrylamide derivatives, a new set of coumarin-acrylamide-CA-4 hybrids was designed and synthesized. These compounds were investigated for their cytotoxic activity against cancerous human liver cell line HepG2 cells using 5-fluorouracil...

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Detalles Bibliográficos
Autores principales: Abd El-Lateef, Hany M., Abdel Ghany, Lina M. A., Saleem, Rasha Mohammed, Ahmed Maghrabi, Ali Hassan, Yahya Alahdal, Maryam Abdulrahman, Khalifa Ali, Eman Hussain, Beshay, Botros Y., Zaki, Islam, Masoud, Reham E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626558/
https://www.ncbi.nlm.nih.gov/pubmed/37936638
http://dx.doi.org/10.1039/d3ra06644d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626558/
https://www.ncbi.nlm.nih.gov/pubmed/37936638
http://dx.doi.org/10.1039/d3ra06644d

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