An exploratory in silico comparison of open-source codon harmonization tools

BACKGROUND: Not changing the native constitution of genes prior to their expression by a heterologous host can affect the amount of proteins synthesized as well as their folding, hampering their activity and even cell viability. Over the past decades, several strategies have been developed to optimi...

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Detalles Bibliográficos
Autores principales: Willems, Thomas, Hectors, Wim, Rombaut, Jeltien, De Rop, Anne-Sofie, Goegebeur, Stijn, Delmulle, Tom, De Mol, Maarten L., De Maeseneire, Sofie L., Soetaert, Wim K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626681/
https://www.ncbi.nlm.nih.gov/pubmed/37932726
http://dx.doi.org/10.1186/s12934-023-02230-y

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