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Bruton’s tyrosine kinase is a possible therapeutic target in microscopic polyangiitis

BACKGROUND: Bruton’s tyrosine kinase (Btk) is an enzyme expressed in leukocytes other than T lymphocytes and plasma cells and involved in B-cell receptor- and Fcγ receptor (FcγR)-mediated signal transduction. Btk inhibitors potentially suppress autoantibody production due to the expected inhibitory...

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Detalles Bibliográficos
Autores principales:	Nakade, Issei, Tamura, Yuto, Hashimoto, Fuyu, Ariza, Yuko, Hotta, Shingo, Fujigaya, Hirofumi, Arai, Suishin, Taniguchi, Mai, Ogawa, Hodaka, Nishibata, Yuka, Masuda, Sakiko, Nakazawa, Daigo, Tomaru, Utano, Ishizu, Akihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626711/ https://www.ncbi.nlm.nih.gov/pubmed/37932784 http://dx.doi.org/10.1186/s13075-023-03201-9

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