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Isthmin-1 attenuates allergic Asthma by stimulating adiponectin expression and alveolar macrophage efferocytosis in mice
BACKGROUND: Allergic asthma is a common respiratory disease that significantly impacts human health. Through in silico analysis of human lung RNASeq, we found that asthmatic lungs display lower levels of Isthmin-1 (ISM1) expression than healthy lungs. ISM1 is an endogenous anti-inflammatory protein...
Autores principales: | Tee, Jong Huat, Vijayakumar, Udhaya, Shanmugasundaram, Mahalakshmi, Lam, Terence Y. W., Liao, Wupeng, Yang, Yuansheng, Wong, W. S. Fred, Ge, Ruowen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626717/ https://www.ncbi.nlm.nih.gov/pubmed/37932719 http://dx.doi.org/10.1186/s12931-023-02569-1 |
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