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Isthmin-1 attenuates allergic Asthma by stimulating adiponectin expression and alveolar macrophage efferocytosis in mice

BACKGROUND: Allergic asthma is a common respiratory disease that significantly impacts human health. Through in silico analysis of human lung RNASeq, we found that asthmatic lungs display lower levels of Isthmin-1 (ISM1) expression than healthy lungs. ISM1 is an endogenous anti-inflammatory protein...

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Detalles Bibliográficos
Autores principales: Tee, Jong Huat, Vijayakumar, Udhaya, Shanmugasundaram, Mahalakshmi, Lam, Terence Y. W., Liao, Wupeng, Yang, Yuansheng, Wong, W. S. Fred, Ge, Ruowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626717/
https://www.ncbi.nlm.nih.gov/pubmed/37932719
http://dx.doi.org/10.1186/s12931-023-02569-1

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