PER2 binding to HSP90 enhances immune response against oral squamous cell carcinoma by inhibiting IKK/NF-κB pathway and PD-L1 expression

BACKGROUND: Programmed death-ligand 1 (PD-L1) contributes to the immune escape of tumor cells and is a critical target for antitumor immunotherapy. However, the molecular mechanisms regulating PD-L1 expression remain unclear, hindering the development of effective therapies. Here we investigate the...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiwei, Sun, Deping, Tang, Hong, Ren, Jie, Yin, Shilin, Yang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626827/
https://www.ncbi.nlm.nih.gov/pubmed/37914384
http://dx.doi.org/10.1136/jitc-2023-007627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626827/
https://www.ncbi.nlm.nih.gov/pubmed/37914384
http://dx.doi.org/10.1136/jitc-2023-007627

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