2-[4-(2-Chloro­benz­yl)-3-methyl-6-oxo-1,6-di­hydro­pyridazin-1-yl]-N-(4-fluoro­phen­yl)acetamide

The conformation of the title mol­ecule, C(20)H(17)ClFN(3)O(2), is partly determined by an intra­molecular C—H⋯O hydrogen bond, which leads to a dihedral angle of 14.7 (4)° between the fluoro­benzene ring and the acetamide group. The 2-chloro­benzyl group is rotationally disordered over two orientat...

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Detalles Bibliográficos
Autores principales: Assila, Hamza, Ameziane El Hassani, Issam, El Moutaouakil Ala Allah, Abderrazzak, Alsubari, Abdulsalam, Mague, Joel T, Ramli, Youssef, Ansar, MHammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Data Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626847/
https://www.ncbi.nlm.nih.gov/pubmed/37936589
http://dx.doi.org/10.1107/S241431462300901X
Descripción
Sumario:The conformation of the title mol­ecule, C(20)H(17)ClFN(3)O(2), is partly determined by an intra­molecular C—H⋯O hydrogen bond, which leads to a dihedral angle of 14.7 (4)° between the fluoro­benzene ring and the acetamide group. The 2-chloro­benzyl group is rotationally disordered over two orientations in a 0.656 (2): 0.344 (2) ratio. In the crystal, a layered structure is formed by N—H⋯O, C—H⋯O and C—H⋯F hydrogen bonds plus slipped π–π stacking inter­actions. [Image: see text]

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