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6,7-Diphenyl-5-thia-7-aza­spiro­[2.6]nonan-8-one 5,5-dioxide

The racemic mixture of the title compound, C(19)H(19)NO(3)S, crystallizes in space group P [Image: see text] with two homochiral mol­ecules in each asymmetric unit. The seven-membered ring in both mol­ecules is in a pucker-chair conformation. The extended structure exhibits C—H⋯O hydrogen bonds, of...

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Detalles Bibliográficos
Autores principales: Yennawar, Hemant P., Russell, Michael W., Silverberg, Lee J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626852/
https://www.ncbi.nlm.nih.gov/pubmed/37936592
http://dx.doi.org/10.1107/S2414314623009379
Descripción
Sumario:The racemic mixture of the title compound, C(19)H(19)NO(3)S, crystallizes in space group P [Image: see text] with two homochiral mol­ecules in each asymmetric unit. The seven-membered ring in both mol­ecules is in a pucker-chair conformation. The extended structure exhibits C—H⋯O hydrogen bonds, of which two connect crystallographically independent mol­ecules to generate a chain propagating along the b-axis direction. One C—H grouping of the cyclo­propyl ring is in close contact with the phenyl ring of the neighboring independent mol­ecule in C—H⋯π type inter­actions with carbon atom–ring-centroid distances of 3.544 (5) and 3.596 (4) Å. Other inter­actions are of the parallel–reciprocal type, with the chiral carbon atom of one mol­ecule donating a proton to an oxygen atom of the sulfone group of a symmetry-related mol­ecule and vice-versa. Symmetry-related mol­ecular pairs also exhibit T-type inter­actions between aromatic rings with inter­planar angles of 74.2 (2) and 69.2 (2)° and inter­centroid distances of 4.965 (4) and 5.114 (4) Å. [Image: see text]