Synthesis, crystal structure and in vitro anti-proliferative activity of 2-[(4-acetyl­phen­yl)carbamo­yl]phenyl acetate

2-[(4-Acetyl­phen­yl)carbamo­yl]phenyl acetate, C(17)H(15)NO(4), has been synthesized and structurally characterized. In the structure, N—H⋯O hydrogen-bonding inter­actions form chains of mol­ecules aligned along the [101] direction. The chains are linked by π–π and C—H⋯π inter­actions, forming a th...

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Detalles Bibliográficos
Autores principales: Mohamed-Ezzat, Reham A., Kariuki, Benson M., Srour, Aladdin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626967/
https://www.ncbi.nlm.nih.gov/pubmed/37936857
http://dx.doi.org/10.1107/S2056989023008526
Descripción
Sumario:2-[(4-Acetyl­phen­yl)carbamo­yl]phenyl acetate, C(17)H(15)NO(4), has been synthesized and structurally characterized. In the structure, N—H⋯O hydrogen-bonding inter­actions form chains of mol­ecules aligned along the [101] direction. The chains are linked by π–π and C—H⋯π inter­actions, forming a three dimensional network. The compound has been screened for in vitro anti-proliferative activity revealing considerable activity.

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