Cargando…

Interleukin-27 tackles immunosuppression in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the western world. It is characterized by a high dependency on interactions with the surrounding immune landscape, highlighting its suitability for immune-mediated therapeutic interventions. We recently revealed that the cytokin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fernandez Botana, Iria, Pagano, Giulia, Moussay, Etienne, Paggetti, Jerome
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Author’s View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627055/ https://www.ncbi.nlm.nih.gov/pubmed/37937211 http://dx.doi.org/10.1080/2162402X.2023.2276490

Ejemplares similares

High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia
por: Wierz, Marina, et al.
Publicado: (2018)

Small extracellular vesicles: multi-faceted tools for leukemia immune evasion in vivo
por: Gargiulo, Ernesto, et al.
Publicado: (2022)

Method for the Analysis of the Tumor Microenvironment by Mass Cytometry: Application to Chronic Lymphocytic Leukemia
por: Gonder, Susanne, et al.
Publicado: (2020)

Interleukin-27 potentiates CD8(+) T-cell-mediated antitumor immunity in chronic lymphocytic leukemia
por: Pagano, Giulia, et al.
Publicado: (2023)

The Tumor Microenvironment-Dependent Transcription Factors AHR and HIF-1α Are Dispensable for Leukemogenesis in the Eµ-TCL1 Mouse Model of Chronic Lymphocytic Leukemia
por: Gonder, Susanne, et al.
Publicado: (2021)

Driving Natural Killer cells toward the melanoma tumor battlefield: Autophagy as a valuable therapeutic target
por: Noman, Muhammad Zaeem, et al.
Publicado: (2018)

Targeting mRNA translation aberrations: A novel approach for therapy in chronic lymphocytic leukemia
por: Klapp, Vanessa, et al.
Publicado: (2023)

Sugars boost exhausted tumor-infiltrating lymphocytes by counteracting immunosuppressive activities of galectins
por: Gordon-Alonso, Monica, et al.
Publicado: (2014)

Understanding anti-leukemia responses to donor lymphocyte infusion
por: Bachireddy, Pavan, et al.
Publicado: (2014)

The B-Side of Cancer Immunity: The Underrated Tune
por: Largeot, Anne, et al.
Publicado: (2019)

Lymphocyte-derived interleukin-17A adds another brick in the wall of inflammation-induced breast carcinogenesis
por: Bastid, Jérémy, et al.
Publicado: (2014)

Survivin the battle against immunosuppression
por: Manuel, Edwin R., et al.
Publicado: (2012)

Expand to shield: IL-15 and in situ lymphocytic proliferation
por: Bindea, Gabriela, et al.
Publicado: (2021)

Thwarting galectin-induced immunosuppression in breast cancer
por: Salatino, Mariana, et al.
Publicado: (2013)

The role of soluble CD40L in immunosuppression
por: Schlom, Jeffrey, et al.
Publicado: (2013)

Hypoxia-driven immunosuppression contributes to the pre-metastatic niche
por: Sceneay, Jaclyn, et al.
Publicado: (2013)

REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer
por: Folch-Puy, Emma
Publicado: (2013)

Non-replicating Toxoplasma gondii reverses tumor-associated immunosuppression
por: Fox, Barbara A, et al.
Publicado: (2013)

Blockade of PD-1 immunosuppression boosts CAR T-cell therapy
por: John, Liza B, et al.
Publicado: (2013)

Forging a link between oncogenic signaling and immunosuppression in melanoma
por: Khalili, Jahan S., et al.
Publicado: (2013)

Modulating CD27 signaling to treat cancer
por: Riether, Carsten, et al.
Publicado: (2012)

New strategies for melanoma immunotherapy: How to overcome immunosuppression in the tumor microenvironment
por: Umansky, Viktor
Publicado: (2012)

‘Hardcore’ OX40(+) immunosuppressive regulatory T cells in hepatic cirrhosis and cancer
por: Piconese, Silvia, et al.
Publicado: (2014)

Overcoming immunosuppression as a new immunotherapeutic approach against pancreatic cancer
por: Bazhin, Alexandr V, et al.
Publicado: (2013)

Contribution of regulatory T cells to immunosuppression and disease progression in multiple myeloma patients
por: Raja, Karthick Raja Muthu, et al.
Publicado: (2013)

P598: DISRUPTION IN ONE-CARBON METABOLISM THROUGH MTHFD1 INHIBITION AS NOVEL THERAPEUTIC STRATEGY IN CHRONIC LYMPHOCYTIC LEUKEMIA
por: Viry, Elodie, et al.
Publicado: (2023)

IFNα induces prolonged remissions modeling curative immunologic responses in chronic myeloid leukemia
por: Ilander, Mette, et al.
Publicado: (2014)

Dendritic cells matured in the presence of TLR ligands overcome the immunosuppressive functions of regulatory T cells
por: Berk, Erik, et al.
Publicado: (2014)

The fatal alliance of cancer and T cells: How pancreatic tumor cells gather immunosuppressive T cells
por: Grage-Griebenow, Evelin, et al.
Publicado: (2014)

High immunosuppressive burden in advanced hepatocellular carcinoma patients: Can effector functions be restored?
por: Lugade, Amit A, et al.
Publicado: (2013)

High-density lipoproteins delivering interleukin-15
por: Ochoa, Maria C., et al.
Publicado: (2013)

Pancreatic cancer-associated stellate cells: A viable target for reducing immunosuppression in the tumor microenvironment
por: Mace, Thomas A, et al.
Publicado: (2013)

Could the properties of IL-27 make it an ideal adjuvant for anticancer immunotherapy?
por: Swarbrick, Alexander, et al.
Publicado: (2013)

Invariant natural killer T cells reconstitution and the control of leukemia relapse in pediatric haploidentical hematopoietic stem cell transplantation
por: Casorati, Giulia, et al.
Publicado: (2012)

Hematological Malignancy-Derived Small Extracellular Vesicles and Tumor Microenvironment: The Art of Turning Foes into Friends
por: Gargiulo, Ernesto, et al.
Publicado: (2019)

Editorial: New Insights Into the Complexity of Tumor Immunology in B-Cell Malignancies: Prognostic and Predictive Biomarkers and Therapy
por: Moussay, Etienne, et al.
Publicado: (2022)

Editorial: New Insights into the Complexity of Tumor Immunology in B-cell Malignancies: Tumor Immunology and Immunotherapy
por: Seiffert, Martina, et al.
Publicado: (2022)

Editorial: New Insights Into the Complexity of Tumor Immunology in B-Cell Malignancies: Disease Biology and Signaling
por: Paggetti, Jérôme, et al.
Publicado: (2021)

The dual targeting of immunosuppressive cells and oxidants promotes effector and memory T-cell functions against lung cancer
por: Sawant, Anandi, et al.
Publicado: (2014)

A novel miRNA-mediated STOP sign in lung cancer: miR-340 inhibits the proliferation of lung cancer cells through p27(KIP1)
por: Fernandez, Serena, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_rp0acs76095gthntbkskdr7nn9