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An experimental workflow for identifying RNA m(6)A alterations in cellular senescence by methylated RNA immunoprecipitation sequencing

N(6)-methyladenosine (m(6)A), the most prevalent mRNA modification in eukaryotic cells, is known to play regulatory roles in a wide array of biological processes, including aging and cellular senescence. To investigate such roles, the m(6)A modification can be identified across the entire transcript...

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Detalles Bibliográficos
Autores principales: Shi, Yue, Wu, Zeming, Zhang, Weiqi, Qu, Jing, Ci, Weimin, Liu, Guang-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Biological Methods 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627084/
https://www.ncbi.nlm.nih.gov/pubmed/37937255
http://dx.doi.org/10.14440/jbm.2023.403