Cargando…

A Single-Step Immunocapture Assay to Quantify HCC Exosomes Using the Highly Sensitive Fluorescence Nanoparticle-Tracking Analysis

INTRODUCTION: Extracellular vesicles could serve as a non-invasive biomarker for early cancer detection. However, limited methods to quantitate cancer-derived vesicles in the native state remain a significant barrier to clinical translation. AIM: This research aims to develop a rapid, one-step immun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koksal, Ali Riza, Ekmen, Nergiz, Aydin, Yucel, Nunez, Kelley, Sandow, Tyler, Delk, Molly, Moehlen, Martin, Thevenot, Paul, Cohen, Ari, Dash, Srikanta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627088/ https://www.ncbi.nlm.nih.gov/pubmed/37936599 http://dx.doi.org/10.2147/JHC.S423043

Ejemplares similares

Impaired Autophagy Response in Hepatocellular Carcinomas Enriches Glypican-3 in Exosomes, Not in the Microvesicles
por: Koksal, Ali Riza, et al.
Publicado: (2022)

Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis
por: Aydin, Yucel, et al.
Publicado: (2021)

Targeting ER stress/PKA/GSK-3β/β-catenin pathway as a potential novel strategy for hepatitis C virus-infected patients
por: Lin, Dong, et al.
Publicado: (2023)

Immunocapture-based ELISA to characterize and quantify exosomes in both cell culture supernatants and body fluids
por: Logozzi, Mariantonia, et al.
Publicado: (2020)

Distinct Gene Expression Profiles in Viable Hepatocellular Carcinoma Treated With Liver-Directed Therapy
por: Núñez, Kelley G., et al.
Publicado: (2022)

Additional Inhibition of Wnt/β-Catenin Signaling by Metformin in DAA Treatments as a Novel Therapeutic Strategy for HCV-Infected Patients
por: Lin, Dong, et al.
Publicado: (2021)

Hypoalbuminemia Is a Hepatocellular Carcinoma Independent Risk Factor for Tumor Progression in Low-Risk Bridge to Transplant Candidates
por: Núñez, Kelley G., et al.
Publicado: (2022)

PD-1 expression in hepatocellular carcinoma predicts liver-directed therapy response and bridge-to-transplant survival
por: Núñez, Kelley G., et al.
Publicado: (2021)

Immunocapture strategies in translational proteomics
por: Fredolini, Claudia, et al.
Publicado: (2016)

Baseline Alpha-Fetoprotein, Alpha-Fetoprotein-L3, and Des-Gamma-Carboxy Prothrombin Biomarker Status in Bridge to Liver Transplant Outcomes for Hepatocellular Carcinoma
por: Núñez, Kelley G., et al.
Publicado: (2021)

Interferon‐alpha‐induced hepatitis C virus clearance restores p53 tumor suppressor more than direct‐acting antivirals
por: Aydin, Yucel, et al.
Publicado: (2017)

Extracellular Vesicle Release Promotes Viral Replication during Persistent HCV Infection
por: Aydin, Yucel, et al.
Publicado: (2021)

Hepatic Stress Response in HCV Infection Promotes STAT3-Mediated Inhibition of HNF4A-miR-122 Feedback Loop in Liver Fibrosis and Cancer Progression
por: Aydin, Yucel, et al.
Publicado: (2019)

Validation of α‐Synuclein in L1CAM‐Immunocaptured Exosomes as a Biomarker for the Stratification of Parkinsonian Syndromes
por: Jiang, Cheng, et al.
Publicado: (2021)

Chaperone-Mediated Autophagy in the Liver: Good or Bad?
por: Dash, Srikanta, et al.
Publicado: (2019)

Evaluation of Non-invasive Fibrosis Markers in Predicting Esophageal Variceal Bleeding
por: Cifci, Sami, et al.
Publicado: (2021)

Alternating Magnetic Field-Promoted Nanoparticle Mixing: The On-Chip Immunocapture of Serum Neuronal Exosomes for Parkinson’s Disease Diagnostics
por: Sharafeldin, Mohamed, et al.
Publicado: (2023)

High-Efficiency Plasma Separator Based on Immunocapture and Filtration
por: Su, Xiaosong, et al.
Publicado: (2020)

Clinical application of a microfluidic chip for immunocapture and quantification of circulating exosomes to assist breast cancer diagnosis and molecular classification
por: Fang, Shimeng, et al.
Publicado: (2017)

The Role of e-NOS in Chronic Cholestasis-Induced Liver and Renal Injury in Rats: The Effect of N-Acetyl Cysteine
por: Gunay, Yusuf, et al.
Publicado: (2014)

Hepatocellular Carcinoma Mechanisms Associated with Chronic HCV Infection and the Impact of Direct-Acting Antiviral Treatment
por: Dash, Srikanta, et al.
Publicado: (2020)

Microparticle immunocapture assay for quantitation of protein multimer amount and size
por: Gutknecht, Michael F., et al.
Publicado: (2022)

Complement Activation in Liver Transplantation: Role of Donor Macrosteatosis and Implications in Delayed Graft Function
por: Núñez, Kelley, et al.
Publicado: (2018)

Selective immunocapture reveals neoplastic human mast cells secrete distinct microvesicle‐ and exosome‐like populations of KIT‐containing extracellular vesicles
por: Pfeiffer, Annika, et al.
Publicado: (2022)

Immunocapture and Identification of Cell Membrane Protein Antigenic Targets of Serum Autoantibodies
por: Littleton, Edward, et al.
Publicado: (2009)

Development of Immunocapture-LC/MS Assay for Simultaneous ADA Isotyping and Semiquantitation
por: Chen, Lin-Zhi, et al.
Publicado: (2016)

Online immunocapture ICP-MS for the determination of the metalloprotein ceruloplasmin in human serum
por: Bernevic, Bogdan, et al.
Publicado: (2018)

Selective immunocapture and light-controlled traceless release of transiently caged proteins
por: Rakauskaitė, Rasa, et al.
Publicado: (2021)

Use of an immunocapture device to detect cytokine release in discrete brain regions
por: Frank, Matthew G., et al.
Publicado: (2023)

Efficient release of immunocaptured cells using coiled-coils in a microfluidic device
por: Zhang, Mengen, et al.
Publicado: (2019)

Nanomaterial-Based Immunocapture Platforms for the Recognition, Isolation, and Detection of Circulating Tumor Cells
por: Liu, Yichao, et al.
Publicado: (2022)

Effects of sample matrix in the measurement of antithrombin by LC-MS: A role for immunocapture
por: Kruijt, M., et al.
Publicado: (2023)

Development and Application of an Immunocapture PCR Diagnostic Assay Based on the Monoclonal Antibody for the Detection of Shigella
por: Zhang, Liding, et al.
Publicado: (2020)

Measurement of Microcystin Activity in Human Plasma Using Immunocapture and Protein Phosphatase Inhibition Assay
por: Cunningham, Brady R., et al.
Publicado: (2022)

Autophagy in hepatocellular carcinomas: from pathophysiology to therapeutic response
por: Dash, Srikanta, et al.
Publicado: (2016)

Links between donor macrosteatosis, interleukin-33 and complement after liver transplantation
por: Núñez, Kelley, et al.
Publicado: (2020)

Detection of Shigella in Milk and Clinical Samples by Magnetic Immunocaptured-Loop-Mediated Isothermal Amplification Assay
por: Zhang, Liding, et al.
Publicado: (2018)

Measurement of Microcystin and Nodularin Activity in Human Urine by Immunocapture-Protein Phosphatase 2A Assay
por: Wharton, Rebekah E., et al.
Publicado: (2019)

Isotyping and Semi-Quantitation of Monkey Anti-Drug Antibodies by Immunocapture Liquid Chromatography-Mass Spectrometry
por: Huang, Xiaoxiao, et al.
Publicado: (2021)

On the spot immunocapture in targeted biomarker analysis using paper-bound streptavidin as anchor for biotinylated antibodies
por: Johannsen, Christina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_l18lturtj1m3tu2hk1lo3vocck