Multi-omics for COVID-19: driving development of therapeutics and vaccines

The ongoing COVID-19 pandemic caused by SARS-CoV-2 has raised global concern for public health and economy. The development of therapeutics and vaccines to combat this virus is continuously progressing. Multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, epigenomic...

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Detalles Bibliográficos
Autores principales: Guo, Mengyu, Xiong, Muya, Peng, Jinying, Guan, Tong, Su, Haixia, Huang, Yanyi, Yang, Cai-Guang, Li, Yang, Boraschi, Diana, Pillaiyar, Thanigaimalai, Wang, Guanbo, Yi, Chengqi, Xu, Yechun, Chen, Chunying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627145/
https://www.ncbi.nlm.nih.gov/pubmed/37936830
http://dx.doi.org/10.1093/nsr/nwad161
Descripción
Sumario:The ongoing COVID-19 pandemic caused by SARS-CoV-2 has raised global concern for public health and economy. The development of therapeutics and vaccines to combat this virus is continuously progressing. Multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, epigenomics and metallomics, have helped understand the structural and molecular features of the virus, thereby assisting in the design of potential therapeutics and accelerating vaccine development for COVID-19. Here, we provide an up-to-date overview of the latest applications of multi-omics technologies in strategies addressing COVID-19, in order to provide suggestions towards the development of highly effective knowledge-based therapeutics and vaccines.

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