Multi-omics for COVID-19: driving development of therapeutics and vaccines

The ongoing COVID-19 pandemic caused by SARS-CoV-2 has raised global concern for public health and economy. The development of therapeutics and vaccines to combat this virus is continuously progressing. Multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, epigenomic...

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Autores principales: Guo, Mengyu, Xiong, Muya, Peng, Jinying, Guan, Tong, Su, Haixia, Huang, Yanyi, Yang, Cai-Guang, Li, Yang, Boraschi, Diana, Pillaiyar, Thanigaimalai, Wang, Guanbo, Yi, Chengqi, Xu, Yechun, Chen, Chunying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627145/
https://www.ncbi.nlm.nih.gov/pubmed/37936830
http://dx.doi.org/10.1093/nsr/nwad161
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author Guo, Mengyu
Xiong, Muya
Peng, Jinying
Guan, Tong
Su, Haixia
Huang, Yanyi
Yang, Cai-Guang
Li, Yang
Boraschi, Diana
Pillaiyar, Thanigaimalai
Wang, Guanbo
Yi, Chengqi
Xu, Yechun
Chen, Chunying
author_facet Guo, Mengyu
Xiong, Muya
Peng, Jinying
Guan, Tong
Su, Haixia
Huang, Yanyi
Yang, Cai-Guang
Li, Yang
Boraschi, Diana
Pillaiyar, Thanigaimalai
Wang, Guanbo
Yi, Chengqi
Xu, Yechun
Chen, Chunying
author_sort Guo, Mengyu
collection PubMed
description The ongoing COVID-19 pandemic caused by SARS-CoV-2 has raised global concern for public health and economy. The development of therapeutics and vaccines to combat this virus is continuously progressing. Multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, epigenomics and metallomics, have helped understand the structural and molecular features of the virus, thereby assisting in the design of potential therapeutics and accelerating vaccine development for COVID-19. Here, we provide an up-to-date overview of the latest applications of multi-omics technologies in strategies addressing COVID-19, in order to provide suggestions towards the development of highly effective knowledge-based therapeutics and vaccines.
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spelling pubmed-106271452023-11-07 Multi-omics for COVID-19: driving development of therapeutics and vaccines Guo, Mengyu Xiong, Muya Peng, Jinying Guan, Tong Su, Haixia Huang, Yanyi Yang, Cai-Guang Li, Yang Boraschi, Diana Pillaiyar, Thanigaimalai Wang, Guanbo Yi, Chengqi Xu, Yechun Chen, Chunying Natl Sci Rev Review The ongoing COVID-19 pandemic caused by SARS-CoV-2 has raised global concern for public health and economy. The development of therapeutics and vaccines to combat this virus is continuously progressing. Multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, epigenomics and metallomics, have helped understand the structural and molecular features of the virus, thereby assisting in the design of potential therapeutics and accelerating vaccine development for COVID-19. Here, we provide an up-to-date overview of the latest applications of multi-omics technologies in strategies addressing COVID-19, in order to provide suggestions towards the development of highly effective knowledge-based therapeutics and vaccines. Oxford University Press 2023-05-30 /pmc/articles/PMC10627145/ /pubmed/37936830 http://dx.doi.org/10.1093/nsr/nwad161 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of China Science Publishing & Media Ltd. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Guo, Mengyu
Xiong, Muya
Peng, Jinying
Guan, Tong
Su, Haixia
Huang, Yanyi
Yang, Cai-Guang
Li, Yang
Boraschi, Diana
Pillaiyar, Thanigaimalai
Wang, Guanbo
Yi, Chengqi
Xu, Yechun
Chen, Chunying
Multi-omics for COVID-19: driving development of therapeutics and vaccines
title Multi-omics for COVID-19: driving development of therapeutics and vaccines
title_full Multi-omics for COVID-19: driving development of therapeutics and vaccines
title_fullStr Multi-omics for COVID-19: driving development of therapeutics and vaccines
title_full_unstemmed Multi-omics for COVID-19: driving development of therapeutics and vaccines
title_short Multi-omics for COVID-19: driving development of therapeutics and vaccines
title_sort multi-omics for covid-19: driving development of therapeutics and vaccines
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627145/
https://www.ncbi.nlm.nih.gov/pubmed/37936830
http://dx.doi.org/10.1093/nsr/nwad161
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