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CRISPR screen identifies CEBPB as contributor to dyskeratosis congenita fibroblast senescence via augmented inflammatory gene response

Aging is the consequence of intra- and extracellular events that promote cellular senescence. Dyskeratosis congenita (DC) is an example of a premature aging disorder caused by underlying telomere/telomerase-related mutations. Cells from these patients offer an opportunity to study telomere-related a...

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Detalles Bibliográficos
Autores principales:	Westin, Erik R, Khodadadi-Jamayran, Alireza, Pham, Linh K, Tung, Moon Ley, Goldman, Frederick D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Mutant Screen Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627266/ https://www.ncbi.nlm.nih.gov/pubmed/37717172 http://dx.doi.org/10.1093/g3journal/jkad207

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