fastlin: an ultra-fast program for Mycobacterium tuberculosis complex lineage typing

SUMMARY: Fastlin is a bioinformatics tool designed for rapid Mycobacterium tuberculosis complex (MTBC) lineage typing. It utilizes an ultra-fast alignment-free approach to detect previously identified barcode single nucleotide polymorphisms associated with specific MTBC lineages. In a comprehensive...

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Detalles Bibliográficos
Autores principales: Derelle, Romain, Lees, John, Phelan, Jody, Lalvani, Ajit, Arinaminpathy, Nimalan, Chindelevitch, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627351/
https://www.ncbi.nlm.nih.gov/pubmed/37871178
http://dx.doi.org/10.1093/bioinformatics/btad648
Descripción
Sumario:SUMMARY: Fastlin is a bioinformatics tool designed for rapid Mycobacterium tuberculosis complex (MTBC) lineage typing. It utilizes an ultra-fast alignment-free approach to detect previously identified barcode single nucleotide polymorphisms associated with specific MTBC lineages. In a comprehensive benchmarking against existing tools, fastlin demonstrated high accuracy and significantly faster running times. AVAILABILITY AND IMPLEMENTATION: fastlin is freely available at https://github.com/rderelle/fastlin and can easily be installed using Conda.

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