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Single-tube multiplex real-time PCR with EvaGreen and high-resolution melting analysis for diagnosis of α(0)-thalassemia--(SEA),--(THAI), and--(CR) type deletions
Regions with a high prevalence of α-thalassemia (α-thal) require simple, rapid, and accurate tests for carrier screening and prenatal diagnosis. Diagnosis of multiple deletions in a single tube is necessary to clearly identify individuals with α(0)-thalassemia in the routine setting, especially in a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627449/ https://www.ncbi.nlm.nih.gov/pubmed/37930985 http://dx.doi.org/10.1371/journal.pone.0293838 |