Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile

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Clostridioides difficile produces toxins that damage the colonic epithelium, causing colitis. Variation in disease severity is poorly understood and has been attributed to host factors and virulence differences between C. difficile strains. We test 23 epidemic ST1 C. difficile clinical isolates for...

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Detalles Bibliográficos
Autores principales: Dong, Qiwen, Lin, Huaiying, Allen, Marie-Maude, Garneau, Julian R., Sia, Jonathan K., Smith, Rita C., Haro, Fidel, McMillen, Tracy, Pope, Rosemary L., Metcalfe, Carolyn, Burgo, Victoria, Woodson, Che, Dylla, Nicholas, Kohout, Claire, Sundararajan, Anitha, Snitkin, Evan S., Young, Vincent B., Fortier, Louis-Charles, Kamboj, Mini, Pamer, Eric G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627504/
https://www.ncbi.nlm.nih.gov/pubmed/37523264
http://dx.doi.org/10.1016/j.celrep.2023.112861
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